Zinc in PDB 6dbu: Cryo-Em Structure of Rag in Complex with 12-Rss and 23-Rss Substrate Dnas

All present enzymatic activity of Cryo-Em Structure of Rag in Complex with 12-Rss and 23-Rss Substrate Dnas:
2.3.2.27;

The structure of Cryo-Em Structure of Rag in Complex with 12-Rss and 23-Rss Substrate Dnas also contains other interesting chemical elements:

Calcium

(Ca)

4 atoms

The binding sites of Zinc atom in the Cryo-Em Structure of Rag in Complex with 12-Rss and 23-Rss Substrate Dnas (pdb code 6dbu). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Cryo-Em Structure of Rag in Complex with 12-Rss and 23-Rss Substrate Dnas, PDB code: 6dbu:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Cryo-Em Structure of Rag in Complex with 12-Rss and 23-Rss Substrate Dnas


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Cryo-Em Structure of Rag in Complex with 12-Rss and 23-Rss Substrate Dnas within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1101 b:52.3 occ:1.00 NE2 A:HIS959 2.0 42.3 1.0 NE2 A:HIS964 2.1 55.0 1.0 CE1 A:HIS964 2.1 51.3 1.0 SG A:CYS749 2.3 43.5 1.0 CE1 A:HIS959 2.8 44.1 1.0 CB A:CYS752 2.9 66.2 1.0 CD2 A:HIS959 3.1 42.1 1.0 N A:CYS752 3.3 55.6 1.0 CB A:CYS749 3.3 45.4 1.0 ND1 A:HIS964 3.4 52.2 1.0 CD2 A:HIS964 3.5 56.0 1.0 CA A:CYS752 3.7 59.1 1.0 ND1 A:HIS959 4.0 40.0 1.0 CG A:HIS964 4.1 56.6 1.0 CG A:HIS959 4.1 39.4 1.0 CB A:LEU751 4.2 48.3 1.0 C A:LEU751 4.3 54.6 1.0 SG A:CYS752 4.4 64.3 1.0 CA A:LEU751 4.6 49.8 1.0 CA A:CYS749 4.7 44.6 1.0 N A:LEU751 4.7 45.7 1.0 CB A:ALA963 4.7 64.6 1.0 CB A:HIS766 4.7 59.5 1.0 C A:CYS752 4.7 55.8 1.0 CD1 A:LEU751 4.8 51.9 1.0 CG A:LEU751 4.8 45.8 1.0

Zinc binding site 2 out of 2 in the Cryo-Em Structure of Rag in Complex with 12-Rss and 23-Rss Substrate Dnas


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Cryo-Em Structure of Rag in Complex with 12-Rss and 23-Rss Substrate Dnas within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn1101 b:51.8 occ:1.00 NE2 C:HIS964 2.0 49.7 1.0 NE2 C:HIS959 2.0 40.7 1.0 SG C:CYS749 2.3 43.0 1.0 CE1 C:HIS964 2.3 53.4 1.0 CB C:CYS752 2.7 66.2 1.0 CE1 C:HIS959 2.8 42.4 1.0 CD2 C:HIS959 3.1 40.5 1.0 CB C:CYS749 3.2 43.6 1.0 N C:CYS752 3.2 54.2 1.0 CD2 C:HIS964 3.3 47.9 1.0 CA C:CYS752 3.5 59.1 1.0 ND1 C:HIS964 3.6 52.6 1.0 ND1 C:HIS959 4.0 37.7 1.0 CG C:HIS964 4.1 52.0 1.0 SG C:CYS752 4.1 64.7 1.0 CG C:HIS959 4.1 38.0 1.0 C C:LEU751 4.4 51.7 1.0 C C:CYS752 4.5 55.4 1.0 CB C:LEU751 4.6 42.1 1.0 CA C:CYS749 4.6 42.6 1.0 CB C:HIS766 4.7 57.8 1.0 N C:LEU751 4.8 42.4 1.0 CA C:LEU751 4.8 46.0 1.0 CD1 C:LEU751 4.9 38.3 1.0

H.Ru, W.Mi, P.Zhang, F.W.Alt, D.G.Schatz, M.Liao, H.Wu. Dna Melting Initiates the Rag Catalytic Pathway. Nat. Struct. Mol. Biol. V. 25 732 2018.
ISSN: ESSN 1545-9985
PubMed: 30061602
DOI: 10.1038/S41594-018-0098-5