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Atomistry » Zinc » PDB 6cen-6clm » 6ck3 » |
Zinc in PDB 6ck3: Co-Crytsal Structure of MNK2 in Complex with An InhibitorEnzymatic activity of Co-Crytsal Structure of MNK2 in Complex with An Inhibitor
All present enzymatic activity of Co-Crytsal Structure of MNK2 in Complex with An Inhibitor:
2.7.11.1; Protein crystallography data
The structure of Co-Crytsal Structure of MNK2 in Complex with An Inhibitor, PDB code: 6ck3
was solved by
Q.Han,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 6ck3:
The structure of Co-Crytsal Structure of MNK2 in Complex with An Inhibitor also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Co-Crytsal Structure of MNK2 in Complex with An Inhibitor
(pdb code 6ck3). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Co-Crytsal Structure of MNK2 in Complex with An Inhibitor, PDB code: 6ck3: Zinc binding site 1 out of 1 in 6ck3Go back to![]() ![]()
Zinc binding site 1 out
of 1 in the Co-Crytsal Structure of MNK2 in Complex with An Inhibitor
![]() Mono view ![]() Stereo pair view
Reference:
S.H.Reich,
P.A.Sprengeler,
G.G.Chiang,
J.R.Appleman,
J.Chen,
J.Clarine,
B.Eam,
J.T.Ernst,
Q.Han,
V.K.Goel,
E.Z.R.Han,
V.Huang,
I.N.J.Hung,
A.Jemison,
K.A.Jessen,
J.Molter,
D.Murphy,
M.Neal,
G.S.Parker,
M.Shaghafi,
S.Sperry,
J.Staunton,
C.R.Stumpf,
P.A.Thompson,
C.Tran,
S.E.Webber,
C.J.Wegerski,
H.Zheng,
K.R.Webster.
Structure-Based Design of Pyridone-Aminal EFT508 Targeting Dysregulated Translation By Selective Mitogen-Activated Protein Kinase Interacting Kinases 1 and 2 (MNK1/2) Inhibition. J. Med. Chem. V. 61 3516 2018.
Page generated: Mon Oct 28 18:55:34 2024
ISSN: ISSN 1520-4804 PubMed: 29526098 DOI: 10.1021/ACS.JMEDCHEM.7B01795 |
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