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Zinc in PDB 6bzo: Mtb Rnap Holo/Rbpa/Fidaxomicin/Upstream Fork Dna

Enzymatic activity of Mtb Rnap Holo/Rbpa/Fidaxomicin/Upstream Fork Dna

All present enzymatic activity of Mtb Rnap Holo/Rbpa/Fidaxomicin/Upstream Fork Dna:
2.7.7.6;

Other elements in 6bzo:

The structure of Mtb Rnap Holo/Rbpa/Fidaxomicin/Upstream Fork Dna also contains other interesting chemical elements:

Magnesium (Mg) 1 atom
Chlorine (Cl) 2 atoms

Zinc Binding Sites:

The binding sites of Zinc atom in the Mtb Rnap Holo/Rbpa/Fidaxomicin/Upstream Fork Dna (pdb code 6bzo). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Mtb Rnap Holo/Rbpa/Fidaxomicin/Upstream Fork Dna, PDB code: 6bzo:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in 6bzo

Go back to Zinc Binding Sites List in 6bzo
Zinc binding site 1 out of 2 in the Mtb Rnap Holo/Rbpa/Fidaxomicin/Upstream Fork Dna


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Mtb Rnap Holo/Rbpa/Fidaxomicin/Upstream Fork Dna within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Zn1401

b:0.3
occ:1.00
SG D:CYS978 2.3 71.9 1.0
SG D:CYS968 2.3 78.0 1.0
SG D:CYS891 2.4 81.7 1.0
SG D:CYS975 2.4 72.3 1.0
CB D:CYS968 3.0 78.0 1.0
CA D:CYS968 3.0 78.0 1.0
CB D:CYS978 3.0 71.9 1.0
CB D:CYS891 3.1 81.7 1.0
N D:ALA969 3.3 77.4 1.0
C D:CYS968 3.7 78.0 1.0
CB D:CYS975 3.9 72.3 1.0
N D:CYS975 4.2 72.3 1.0
N D:CYS968 4.2 78.0 1.0
N D:CYS891 4.3 81.7 1.0
CA D:CYS891 4.3 81.7 1.0
CA D:CYS978 4.4 71.9 1.0
CA D:ALA969 4.5 77.4 1.0
CA D:CYS975 4.6 72.3 1.0
N D:CYS978 4.6 71.9 1.0
N D:THR970 4.7 76.4 1.0
CG2 D:THR893 4.7 86.4 1.0
CB D:ALA969 4.8 77.4 1.0
O D:CYS968 4.9 78.0 1.0
O D:THR967 4.9 75.9 1.0
CG2 D:THR970 5.0 76.4 1.0
O D:CYS975 5.0 72.3 1.0
C D:THR967 5.0 75.9 1.0

Zinc binding site 2 out of 2 in 6bzo

Go back to Zinc Binding Sites List in 6bzo
Zinc binding site 2 out of 2 in the Mtb Rnap Holo/Rbpa/Fidaxomicin/Upstream Fork Dna


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Mtb Rnap Holo/Rbpa/Fidaxomicin/Upstream Fork Dna within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Zn1402

b:0.6
occ:1.00
SG D:CYS60 2.3 82.8 1.0
SG D:CYS78 2.3 81.8 1.0
SG D:CYS75 2.3 84.4 1.0
SG D:CYS62 2.4 82.1 1.0
CB D:CYS60 2.8 82.8 1.0
CB D:CYS75 2.8 84.4 1.0
N D:CYS62 3.5 82.1 1.0
CB D:CYS62 3.7 82.1 1.0
N D:TYR61 3.8 78.9 1.0
N D:GLY63 3.9 81.7 1.0
CB D:CYS78 4.0 81.8 1.0
CA D:CYS60 4.1 82.8 1.0
CA D:CYS62 4.1 82.1 1.0
C D:CYS60 4.3 82.8 1.0
N D:LYS64 4.3 83.9 1.0
N D:CYS78 4.3 81.8 1.0
CA D:CYS75 4.3 84.4 1.0
C D:TYR61 4.5 78.9 1.0
C D:CYS62 4.5 82.1 1.0
CA D:TYR61 4.7 78.9 1.0
CA D:CYS78 4.7 81.8 1.0
CD2 D:TYR65 4.7 84.9 1.0
CB D:LYS64 4.8 83.9 1.0
CA D:GLY63 4.9 81.7 1.0

Reference:

H.Boyaci, J.Chen, M.Lilic, M.Palka, R.A.Mooney, R.Landick, S.A.Darst, E.A.Campbell. Fidaxomicin Jamsmycobacterium Tuberculosisrna Polymerase Motions Needed For Initiation Via Rbpa Contacts. Elife V. 7 2018.
ISSN: ESSN 2050-084X
PubMed: 29480804
DOI: 10.7554/ELIFE.34823
Page generated: Thu Aug 21 12:52:06 2025

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