Zinc in PDB 5w42: Crystal Structure of Human Monoclonal Antibody H3V-47 in Complex with Influenza Virus Hemagglutinin From A/Minnesota/11/2010 (H3N2)

The structure of Crystal Structure of Human Monoclonal Antibody H3V-47 in Complex with Influenza Virus Hemagglutinin From A/Minnesota/11/2010 (H3N2), PDB code: 5w42 was solved by H.Zhang, I.A.Wilson, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	38.92 / 3.57
Space group	P 21 3
Cell size a, b, c (Å), α, β, γ (°)	194.622, 194.622, 194.622, 90.00, 90.00, 90.00
R / Rfree (%)	19.6 / 22.8

The binding sites of Zinc atom in the Crystal Structure of Human Monoclonal Antibody H3V-47 in Complex with Influenza Virus Hemagglutinin From A/Minnesota/11/2010 (H3N2) (pdb code 5w42). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of Human Monoclonal Antibody H3V-47 in Complex with Influenza Virus Hemagglutinin From A/Minnesota/11/2010 (H3N2), PDB code: 5w42:

Zinc binding site 1 out of 1 in the Crystal Structure of Human Monoclonal Antibody H3V-47 in Complex with Influenza Virus Hemagglutinin From A/Minnesota/11/2010 (H3N2)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Human Monoclonal Antibody H3V-47 in Complex with Influenza Virus Hemagglutinin From A/Minnesota/11/2010 (H3N2) within 5.0Å range: probe atom residue distance (Å) B Occ H:Zn301 b:0.2 occ:1.00 SG H:CYS216 3.9 0.8 1.0 CE1 H:HIS218 3.9 0.5 1.0 ND1 H:HIS218 4.2 0.3 1.0 CB H:CYS216 4.7 0.7 1.0 CA H:CYS216 4.9 0.9 1.0

S.Bangaru, H.Zhang, I.M.Gilchuk, T.G.Voss, R.P.Irving, P.Gilchuk, P.Matta, X.Zhu, S.Lang, T.Nieusma, J.A.Richt, R.A.Albrecht, H.A.Vanderven, R.Bombardi, S.J.Kent, A.B.Ward, I.A.Wilson, J.E.Crowe. A Multifunctional Human Monoclonal Neutralizing Antibody That Targets A Unique Conserved Epitope on Influenza Ha. Nat Commun V. 9 2669 2018.
ISSN: ESSN 2041-1723
PubMed: 29991715
DOI: 10.1038/S41467-018-04704-9