Zinc in PDB 5v6a: Crystal Structure of the Middle East Respiratory Syndrome Coronavirus Papain-Like Protease Bound to Ubiquitin Variant Me.2

The structure of Crystal Structure of the Middle East Respiratory Syndrome Coronavirus Papain-Like Protease Bound to Ubiquitin Variant Me.2, PDB code: 5v6a was solved by B.A.Bailey-Elkin, B.L.Mark, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	45.97 / 2.70
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	47.071, 109.779, 183.863, 90.00, 90.00, 90.00
R / Rfree (%)	21.7 / 27.3

The structure of Crystal Structure of the Middle East Respiratory Syndrome Coronavirus Papain-Like Protease Bound to Ubiquitin Variant Me.2 also contains other interesting chemical elements:

Chlorine

(Cl)

4 atoms

The binding sites of Zinc atom in the Crystal Structure of the Middle East Respiratory Syndrome Coronavirus Papain-Like Protease Bound to Ubiquitin Variant Me.2 (pdb code 5v6a). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of the Middle East Respiratory Syndrome Coronavirus Papain-Like Protease Bound to Ubiquitin Variant Me.2, PDB code: 5v6a:

Zinc binding site 1 out of 1 in the Crystal Structure of the Middle East Respiratory Syndrome Coronavirus Papain-Like Protease Bound to Ubiquitin Variant Me.2


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of the Middle East Respiratory Syndrome Coronavirus Papain-Like Protease Bound to Ubiquitin Variant Me.2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1901 b:81.7 occ:1.00 SG A:CYS1709 2.4 73.1 1.0 SG A:CYS1675 2.6 81.0 1.0 SG A:CYS1672 2.6 80.3 1.0 SG A:CYS1707 2.8 72.5 1.0 CB A:CYS1672 3.1 65.1 1.0 CB A:CYS1675 3.4 72.2 1.0 CB A:CYS1707 3.4 64.1 1.0 N A:CYS1675 3.5 83.8 1.0 CB A:CYS1709 3.6 68.3 1.0 CA A:CYS1675 4.1 79.9 1.0 CB A:VAL1674 4.1 76.1 1.0 N A:CYS1709 4.5 74.4 1.0 C A:VAL1674 4.5 82.4 1.0 NH1 A:ARG1713 4.6 64.9 1.0 CA A:CYS1672 4.6 69.1 1.0 N A:VAL1674 4.6 75.8 1.0 CA A:CYS1709 4.6 71.5 1.0 CA A:VAL1674 4.7 77.4 1.0 CG1 A:VAL1674 4.8 76.0 1.0 CA A:CYS1707 4.9 66.9 1.0 C A:CYS1672 4.9 73.0 1.0 CG2 A:VAL1674 5.0 69.5 1.0

W.Zhang, B.A.Bailey-Elkin, R.C.M.Knaap, B.Khare, T.J.Dalebout, G.G.Johnson, P.B.Van Kasteren, N.J.Mcleish, J.Gu, W.He, M.Kikkert, B.L.Mark, S.S.Sidhu. Potent and Selective Inhibition of Pathogenic Viruses By Engineered Ubiquitin Variants. Plos Pathog. V. 13 06372 2017.
ISSN: ESSN 1553-7374
PubMed: 28542609
DOI: 10.1371/JOURNAL.PPAT.1006372