Zinc in PDB 5un7: Structure of the Human POT1-TPP1 Telomeric Complex

The structure of Structure of the Human POT1-TPP1 Telomeric Complex, PDB code: 5un7 was solved by C.Rice, T.Doukov, E.Skordalakes, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 2.10
Space group	P 41 2 2
Cell size a, b, c (Å), α, β, γ (°)	99.530, 99.530, 122.140, 90.00, 90.00, 90.00
R / Rfree (%)	18.2 / 22.2

The structure of Structure of the Human POT1-TPP1 Telomeric Complex also contains other interesting chemical elements:

Potassium

(K)

3 atoms

The binding sites of Zinc atom in the Structure of the Human POT1-TPP1 Telomeric Complex (pdb code 5un7). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Structure of the Human POT1-TPP1 Telomeric Complex, PDB code: 5un7:

Zinc binding site 1 out of 1 in the Structure of the Human POT1-TPP1 Telomeric Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of the Human POT1-TPP1 Telomeric Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn700 b:31.6 occ:1.00 SG A:CYS382 2.3 33.1 1.0 SG A:CYS506 2.3 33.5 1.0 SG A:CYS503 2.3 29.4 1.0 SG A:CYS385 2.3 32.9 1.0 CB A:CYS382 3.2 32.8 1.0 CB A:CYS385 3.2 31.6 1.0 CB A:CYS506 3.3 31.3 1.0 CB A:CYS503 3.3 28.4 1.0 N A:CYS385 3.6 34.0 1.0 N A:CYS506 3.9 33.1 1.0 CA A:CYS385 4.0 33.9 1.0 CA A:CYS506 4.2 32.7 1.0 CD2 A:LEU387 4.4 36.2 1.0 CB A:GLN505 4.4 39.0 1.0 CG A:LEU387 4.5 33.8 1.0 CA A:CYS382 4.6 32.9 1.0 O A:HOH1158 4.7 53.4 1.0 CB A:LYS384 4.7 33.4 1.0 C A:LYS384 4.7 35.8 1.0 CA A:CYS503 4.8 29.2 1.0 C A:GLN505 4.8 34.5 1.0 C A:CYS385 4.8 33.6 1.0 N A:HIS386 5.0 32.7 1.0

C.Rice, P.K.Shastrula, A.V.Kossenkov, R.Hills, D.M.Baird, L.C.Showe, T.Doukov, S.Janicki, E.Skordalakes. Structural and Functional Analysis of the Human POT1-TPP1 Telomeric Complex. Nat Commun V. 8 14928 2017.
ISSN: ESSN 2041-1723
PubMed: 28393830
DOI: 10.1038/NCOMMS14928