Zinc in PDB 5r64: Pandda Analysis Group Deposition -- Crystal Structure of Human Cleavage Factor Im in Complex with FMOPL000464A

The structure of Pandda Analysis Group Deposition -- Crystal Structure of Human Cleavage Factor Im in Complex with FMOPL000464A, PDB code: 5r64 was solved by R.Talon, T.Krojer, L.Diaz-Saez, A.R.Bradley, A.Aimon, M.Fairhead, C.H.Arrowsmith, C.Bountra, A.M.Edwards, K.V.M.Huber, F.Von Delft, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	71.73 / 1.84
Space group	P 32 2 1
Cell size a, b, c (Å), α, β, γ (°)	59.850, 59.850, 215.190, 90.00, 90.00, 120.00
R / Rfree (%)	20.8 / 26

The binding sites of Zinc atom in the Pandda Analysis Group Deposition -- Crystal Structure of Human Cleavage Factor Im in Complex with FMOPL000464A (pdb code 5r64). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 6 binding sites of Zinc where determined in the Pandda Analysis Group Deposition -- Crystal Structure of Human Cleavage Factor Im in Complex with FMOPL000464A, PDB code: 5r64:
Jump to Zinc binding site number: 1; 2; 3; 4; 5; 6;

Zinc binding site 1 out of 6 in the Pandda Analysis Group Deposition -- Crystal Structure of Human Cleavage Factor Im in Complex with FMOPL000464A


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Pandda Analysis Group Deposition -- Crystal Structure of Human Cleavage Factor Im in Complex with FMOPL000464A within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn301 b:0.8 occ:1.00 ND1 A:HIS171 3.0 37.5 1.0 NE1 A:TRP149 3.0 38.8 1.0 O A:HOH526 3.2 53.1 1.0 CE A:MET76 3.3 36.3 1.0 CG A:HIS171 3.4 29.3 1.0 CB A:HIS171 3.6 26.0 1.0 CE1 A:HIS171 3.7 38.2 1.0 SD A:MET76 3.8 36.5 1.0 CE2 A:TRP149 3.9 35.1 1.0 CD1 A:TRP149 4.0 31.1 1.0 O A:HOH473 4.1 50.5 1.0 CZ2 A:TRP149 4.2 42.1 1.0 CD2 A:HIS171 4.2 29.4 1.0 NE2 A:HIS171 4.4 34.4 1.0

Zinc binding site 2 out of 6 in the Pandda Analysis Group Deposition -- Crystal Structure of Human Cleavage Factor Im in Complex with FMOPL000464A


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Pandda Analysis Group Deposition -- Crystal Structure of Human Cleavage Factor Im in Complex with FMOPL000464A within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn302 b:0.2 occ:1.00 ND1 A:HIS89 2.3 33.7 1.0 CG A:HIS89 3.2 30.2 1.0 CE1 A:HIS89 3.3 33.0 1.0 CA A:HIS89 3.4 37.4 1.0 CB A:HIS89 3.4 33.8 1.0 N A:HIS89 4.2 30.6 1.0 O A:HOH482 4.3 45.8 1.0 CD2 A:HIS89 4.4 26.3 1.0 NE2 A:HIS89 4.4 28.0 1.0 C A:HIS89 4.5 37.0 1.0

Zinc binding site 3 out of 6 in the Pandda Analysis Group Deposition -- Crystal Structure of Human Cleavage Factor Im in Complex with FMOPL000464A


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Pandda Analysis Group Deposition -- Crystal Structure of Human Cleavage Factor Im in Complex with FMOPL000464A within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn301 b:33.8 occ:1.00 O B:HOH401 1.4 29.2 1.0 OE1 B:GLU88 2.1 35.6 0.3 NE2 B:HIS93 2.2 28.3 1.0 CD B:GLU88 3.1 37.1 0.3 CE1 B:HIS93 3.1 30.2 1.0 CD2 B:HIS93 3.2 30.7 1.0 CG B:GLU88 3.3 36.9 0.3 OE2 B:GLU88 4.2 38.1 0.3 ND1 B:HIS93 4.2 26.6 1.0 CB B:GLU88 4.2 44.5 0.2 CG B:GLU88 4.3 47.9 0.2 CG B:HIS93 4.3 24.1 1.0 O B:GLU88 4.4 37.2 0.3 CB B:PRO197 4.5 34.5 1.0 CG B:PRO197 4.6 34.0 1.0 ND1 B:HIS89 4.6 46.8 0.3 CE1 B:HIS89 4.8 54.5 0.3 CB B:GLU88 4.8 37.6 0.3 CD B:PRO197 4.9 34.5 1.0

Zinc binding site 4 out of 6 in the Pandda Analysis Group Deposition -- Crystal Structure of Human Cleavage Factor Im in Complex with FMOPL000464A


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Pandda Analysis Group Deposition -- Crystal Structure of Human Cleavage Factor Im in Complex with FMOPL000464A within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn302 b:43.1 occ:1.00 NE2 B:HIS164 1.8 32.0 1.0 CE1 B:HIS164 2.6 40.8 1.0 CD2 B:HIS164 3.0 40.6 1.0 ND1 B:HIS164 3.8 38.9 1.0 CG B:HIS164 4.0 38.7 1.0

Zinc binding site 5 out of 6 in the Pandda Analysis Group Deposition -- Crystal Structure of Human Cleavage Factor Im in Complex with FMOPL000464A


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 5 of Pandda Analysis Group Deposition -- Crystal Structure of Human Cleavage Factor Im in Complex with FMOPL000464A within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn303 b:0.1 occ:1.00 ND1 B:HIS164 3.9 38.9 1.0 CE1 B:HIS164 4.3 40.8 1.0 CG B:HIS164 5.0 38.7 1.0

Zinc binding site 6 out of 6 in the Pandda Analysis Group Deposition -- Crystal Structure of Human Cleavage Factor Im in Complex with FMOPL000464A


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 6 of Pandda Analysis Group Deposition -- Crystal Structure of Human Cleavage Factor Im in Complex with FMOPL000464A within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn304 b:0.2 occ:1.00 NE1 B:TRP149 2.2 38.5 1.0 CD1 B:TRP149 3.1 39.8 1.0 CE2 B:TRP149 3.2 35.6 1.0 ND1 B:HIS171 3.3 41.5 1.0 CG B:HIS171 3.5 34.5 1.0 CZ2 B:TRP149 3.7 41.6 1.0 CE1 B:HIS171 3.8 37.7 1.0 CB B:HIS171 3.8 31.4 1.0 CD2 B:HIS171 4.1 38.8 1.0 SD B:MET76 4.2 43.7 1.0 CE B:MET76 4.2 49.1 1.0 CD1 B:ILE161 4.2 53.8 1.0 NE2 B:HIS171 4.2 39.6 1.0 CG B:TRP149 4.3 37.7 1.0 CD2 B:TRP149 4.4 36.2 1.0 O B:HOH446 4.8 39.1 1.0 CG1 B:ILE161 4.9 47.5 1.0 CA B:HIS171 5.0 26.8 1.0

R.Talon, T.Krojer, L.Diaz-Saez, A.R.Bradley, A.Aimon, M.Fairhead, C.H.Arrowsmith, C.Bountra, A.M.Edwards, K.V.M.Huber, F.Von Delft. Pandda Analysis Group Deposition To Be Published.