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Atomistry » Zinc » PDB 5nsp-5o2e » 5o1c | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Zinc » PDB 5nsp-5o2e » 5o1c » |
Zinc in PDB 5o1c: P53 Cancer Mutant Y220C in Complex with Compound MB184Protein crystallography data
The structure of P53 Cancer Mutant Y220C in Complex with Compound MB184, PDB code: 5o1c
was solved by
A.C.Joerger,
M.G.J.Baud,
M.R.Bauer,
A.R.Fersht,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5o1c:
The structure of P53 Cancer Mutant Y220C in Complex with Compound MB184 also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the P53 Cancer Mutant Y220C in Complex with Compound MB184
(pdb code 5o1c). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the P53 Cancer Mutant Y220C in Complex with Compound MB184, PDB code: 5o1c: Jump to Zinc binding site number: 1; 2; Zinc binding site 1 out of 2 in 5o1cGo back to![]() ![]()
Zinc binding site 1 out
of 2 in the P53 Cancer Mutant Y220C in Complex with Compound MB184
![]() Mono view ![]() Stereo pair view
Zinc binding site 2 out of 2 in 5o1cGo back to![]() ![]()
Zinc binding site 2 out
of 2 in the P53 Cancer Mutant Y220C in Complex with Compound MB184
![]() Mono view ![]() Stereo pair view
Reference:
M.G.J.Baud,
M.R.Bauer,
L.Verduci,
F.A.Dingler,
K.J.Patel,
D.Horil Roy,
A.C.Joerger,
A.R.Fersht.
Aminobenzothiazole Derivatives Stabilize the Thermolabile P53 Cancer Mutant Y220C and Show Anticancer Activity in P53-Y220C Cell Lines. Eur J Med Chem V. 152 101 2018.
Page generated: Sun Oct 27 23:10:22 2024
ISSN: ISSN 1768-3254 PubMed: 29702446 DOI: 10.1016/J.EJMECH.2018.04.035 |
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