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Atomistry » Zinc » PDB 5mcw-5msl » 5mjn » |
Zinc in PDB 5mjn: Three Dimensional Structure of Human Carbonic Anhydrase II in Complex with 5-[(4CHLOROBENZYL)Sulfanyl]Thiophene-2-SulfonamideEnzymatic activity of Three Dimensional Structure of Human Carbonic Anhydrase II in Complex with 5-[(4CHLOROBENZYL)Sulfanyl]Thiophene-2-Sulfonamide
All present enzymatic activity of Three Dimensional Structure of Human Carbonic Anhydrase II in Complex with 5-[(4CHLOROBENZYL)Sulfanyl]Thiophene-2-Sulfonamide:
4.2.1.1; Protein crystallography data
The structure of Three Dimensional Structure of Human Carbonic Anhydrase II in Complex with 5-[(4CHLOROBENZYL)Sulfanyl]Thiophene-2-Sulfonamide, PDB code: 5mjn
was solved by
J.Leitans,
K.Tars,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5mjn:
The structure of Three Dimensional Structure of Human Carbonic Anhydrase II in Complex with 5-[(4CHLOROBENZYL)Sulfanyl]Thiophene-2-Sulfonamide also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Three Dimensional Structure of Human Carbonic Anhydrase II in Complex with 5-[(4CHLOROBENZYL)Sulfanyl]Thiophene-2-Sulfonamide
(pdb code 5mjn). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Three Dimensional Structure of Human Carbonic Anhydrase II in Complex with 5-[(4CHLOROBENZYL)Sulfanyl]Thiophene-2-Sulfonamide, PDB code: 5mjn: Zinc binding site 1 out of 1 in 5mjnGo back to![]() ![]()
Zinc binding site 1 out
of 1 in the Three Dimensional Structure of Human Carbonic Anhydrase II in Complex with 5-[(4CHLOROBENZYL)Sulfanyl]Thiophene-2-Sulfonamide
![]() Mono view ![]() Stereo pair view
Reference:
J.Ivanova,
A.Balode,
R.Zalubovskis,
J.Leitans,
A.Kazaks,
D.Vullo,
K.Tars,
C.T.Supuran.
5-Substituted-Benzylsulfanyl-Thiophene-2-Sulfonamides with Effective Carbonic Anhydrase Inhibitory Activity: Solution and Crystallographic Investigations. Bioorg. Med. Chem. V. 25 857 2017.
Page generated: Sun Oct 27 22:09:34 2024
ISSN: ESSN 1464-3391 PubMed: 28024887 DOI: 10.1016/J.BMC.2016.11.045 |
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