Zinc in PDB 5lxg: Revised Crystal Structure of the Human Adiponectin Receptor 1 in An Open Conformation

The structure of Revised Crystal Structure of the Human Adiponectin Receptor 1 in An Open Conformation, PDB code: 5lxg was solved by C.Leyrat, I.Vasiliauskaite-Brooks, S.Granier, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	26.66 / 2.73
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	92.310, 194.110, 74.330, 90.00, 90.00, 90.00
R / Rfree (%)	22.5 / 23.4

The binding sites of Zinc atom in the Revised Crystal Structure of the Human Adiponectin Receptor 1 in An Open Conformation (pdb code 5lxg). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Revised Crystal Structure of the Human Adiponectin Receptor 1 in An Open Conformation, PDB code: 5lxg:

Zinc binding site 1 out of 1 in the Revised Crystal Structure of the Human Adiponectin Receptor 1 in An Open Conformation


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Revised Crystal Structure of the Human Adiponectin Receptor 1 in An Open Conformation within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn401 b:63.3 occ:1.00 NE2 A:HIS341 2.1 66.3 1.0 NE2 A:HIS337 2.3 67.4 1.0 NE2 A:HIS191 2.3 57.4 1.0 CE1 A:HIS341 2.7 66.1 1.0 CE1 A:HIS337 3.1 67.3 1.0 OG A:SER187 3.3 66.4 1.0 CD2 A:HIS341 3.3 67.5 1.0 CD2 A:HIS191 3.3 57.6 1.0 CE1 A:HIS191 3.3 57.2 1.0 OD2 A:ASP208 3.4 68.9 1.0 CD2 A:HIS337 3.4 68.4 1.0 ND1 A:HIS341 4.0 67.5 1.0 CG A:ASP208 4.2 63.1 1.0 CG A:HIS341 4.2 66.2 1.0 OD1 A:ASP208 4.3 63.7 1.0 ND1 A:HIS337 4.3 68.6 1.0 CG A:HIS191 4.5 55.9 1.0 CG A:HIS337 4.5 67.2 1.0 ND1 A:HIS191 4.5 57.8 1.0 CB A:SER187 4.6 57.6 1.0 O A:HOH545 4.6 56.0 1.0 O A:HOH551 4.7 52.6 1.0 CD2 A:PHE190 4.9 55.9 1.0 O A:SER187 4.9 56.6 1.0

I.Vasiliauskaite-Brooks, R.Sounier, P.Rochaix, G.Bellot, M.Fortier, F.Hoh, L.De Colibus, C.Bechara, E.M.Saied, C.Arenz, C.Leyrat, S.Granier. Structural Insights Into Adiponectin Receptors Suggest Ceramidase Activity. Nature V. 6 120 2017.
ISSN: ISSN 0028-0836
PubMed: 28329765
DOI: 10.1038/NATURE21714