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Atomistry » Zinc » PDB 5j1q-5jf1 » 5jep | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Zinc » PDB 5j1q-5jf1 » 5jep » |
Zinc in PDB 5jep: Human Carbonic Anhydrase II (T199S) Complexed with Benzo[D]Thiazole-2- SulfonamideEnzymatic activity of Human Carbonic Anhydrase II (T199S) Complexed with Benzo[D]Thiazole-2- Sulfonamide
All present enzymatic activity of Human Carbonic Anhydrase II (T199S) Complexed with Benzo[D]Thiazole-2- Sulfonamide:
4.2.1.1; Protein crystallography data
The structure of Human Carbonic Anhydrase II (T199S) Complexed with Benzo[D]Thiazole-2- Sulfonamide, PDB code: 5jep
was solved by
J.M.Fox,
K.Kang,
M.Sastry,
W.Sherman,
B.Sankaran,
P.H.Zwart,
G.M.Whitesides,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Zinc Binding Sites:
The binding sites of Zinc atom in the Human Carbonic Anhydrase II (T199S) Complexed with Benzo[D]Thiazole-2- Sulfonamide
(pdb code 5jep). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Human Carbonic Anhydrase II (T199S) Complexed with Benzo[D]Thiazole-2- Sulfonamide, PDB code: 5jep: Zinc binding site 1 out of 1 in 5jepGo back to![]() ![]()
Zinc binding site 1 out
of 1 in the Human Carbonic Anhydrase II (T199S) Complexed with Benzo[D]Thiazole-2- Sulfonamide
![]() Mono view ![]() Stereo pair view
Reference:
J.M.Fox,
K.Kang,
M.Sastry,
W.Sherman,
B.Sankaran,
P.H.Zwart,
G.M.Whitesides.
Water-Restructuring Mutations Can Reverse the Thermodynamic Signature of Ligand Binding to Human Carbonic Anhydrase. Angew. Chem. Int. Ed. Engl. V. 56 3833 2017.
Page generated: Sun Oct 27 18:46:54 2024
ISSN: ESSN 1521-3773 PubMed: 28252841 DOI: 10.1002/ANIE.201609409 |
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