|
Atomistry » Zinc » PDB 5fpg-5fvv » 5fvr | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Zinc » PDB 5fpg-5fvv » 5fvr » |
Zinc in PDB 5fvr: Structure of Rat Neuronal Nitric Oxide Synthase Heme Domain in Complex with 4-Methyl-6-(2-(5-(1-Methylpiperidin-4-Yl) Pyridin-3-Yl)Ethyl)Pyridin-2-AmineEnzymatic activity of Structure of Rat Neuronal Nitric Oxide Synthase Heme Domain in Complex with 4-Methyl-6-(2-(5-(1-Methylpiperidin-4-Yl) Pyridin-3-Yl)Ethyl)Pyridin-2-Amine
All present enzymatic activity of Structure of Rat Neuronal Nitric Oxide Synthase Heme Domain in Complex with 4-Methyl-6-(2-(5-(1-Methylpiperidin-4-Yl) Pyridin-3-Yl)Ethyl)Pyridin-2-Amine:
1.14.13.39; Protein crystallography data
The structure of Structure of Rat Neuronal Nitric Oxide Synthase Heme Domain in Complex with 4-Methyl-6-(2-(5-(1-Methylpiperidin-4-Yl) Pyridin-3-Yl)Ethyl)Pyridin-2-Amine, PDB code: 5fvr
was solved by
H.Li,
T.L.Poulos,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5fvr:
The structure of Structure of Rat Neuronal Nitric Oxide Synthase Heme Domain in Complex with 4-Methyl-6-(2-(5-(1-Methylpiperidin-4-Yl) Pyridin-3-Yl)Ethyl)Pyridin-2-Amine also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Structure of Rat Neuronal Nitric Oxide Synthase Heme Domain in Complex with 4-Methyl-6-(2-(5-(1-Methylpiperidin-4-Yl) Pyridin-3-Yl)Ethyl)Pyridin-2-Amine
(pdb code 5fvr). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Structure of Rat Neuronal Nitric Oxide Synthase Heme Domain in Complex with 4-Methyl-6-(2-(5-(1-Methylpiperidin-4-Yl) Pyridin-3-Yl)Ethyl)Pyridin-2-Amine, PDB code: 5fvr: Zinc binding site 1 out of 1 in 5fvrGo back to![]() ![]()
Zinc binding site 1 out
of 1 in the Structure of Rat Neuronal Nitric Oxide Synthase Heme Domain in Complex with 4-Methyl-6-(2-(5-(1-Methylpiperidin-4-Yl) Pyridin-3-Yl)Ethyl)Pyridin-2-Amine
![]() Mono view ![]() Stereo pair view
Reference:
H.Wang,
Y.Qin,
H.Li,
L.J.Roman,
P.Martasek,
T.L.Poulos,
R.B.Silverman.
Potent and Selective Human Neuronal Nitric Oxide Synthase Inhibition By Optimization of the 2-Aminopyridine-Based Scaffold with A Pyridine Linker. J.Med.Chem. V. 59 4913 2016.
Page generated: Sun Oct 27 16:33:33 2024
ISSN: ISSN 0022-2623 PubMed: 27050842 DOI: 10.1021/ACS.JMEDCHEM.6B00273 |
Last articlesZn in 9MJ5Zn in 9HNW Zn in 9G0L Zn in 9FNE Zn in 9DZN Zn in 9E0I Zn in 9D32 Zn in 9DAK Zn in 8ZXC Zn in 8ZUF |
© Copyright 2008-2020 by atomistry.com | ||
Home | Site Map | Copyright | Contact us | Privacy |