Zinc in PDB 5e3h: Structural Basis For Rna Recognition and Activation of Rig-I

All present enzymatic activity of Structural Basis For Rna Recognition and Activation of Rig-I:
3.6.4.13;

The structure of Structural Basis For Rna Recognition and Activation of Rig-I, PDB code: 5e3h was solved by F.Jiang, M.T.Miller, J.Marcotrigiano, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	34.97 / 2.70
Space group	P 65 2 2
Cell size a, b, c (Å), α, β, γ (°)	176.030, 176.030, 108.071, 90.00, 90.00, 120.00
R / Rfree (%)	23.4 / 26.8

The structure of Structural Basis For Rna Recognition and Activation of Rig-I also contains other interesting chemical elements:

Fluorine	(F)	3 atoms
Magnesium	(Mg)	3 atoms

The binding sites of Zinc atom in the Structural Basis For Rna Recognition and Activation of Rig-I (pdb code 5e3h). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Structural Basis For Rna Recognition and Activation of Rig-I, PDB code: 5e3h:

Zinc binding site 1 out of 1 in the Structural Basis For Rna Recognition and Activation of Rig-I


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structural Basis For Rna Recognition and Activation of Rig-I within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1001 b:0.8 occ:1.00 SG A:CYS864 2.3 0.9 1.0 SG A:CYS810 2.3 0.3 1.0 SG A:CYS813 2.3 0.7 1.0 SG A:CYS869 2.5 0.9 1.0 CB A:CYS810 3.1 0.1 1.0 CB A:CYS864 3.1 0.9 1.0 CB A:CYS869 3.5 0.8 1.0 CB A:CYS813 3.7 0.8 1.0 N A:CYS813 4.0 0.1 1.0 NE1 A:TRP873 4.1 0.3 1.0 CZ2 A:TRP873 4.4 0.5 1.0 CA A:CYS813 4.4 0.1 1.0 CB A:ARG866 4.5 0.3 1.0 CB A:HIS871 4.5 0.8 1.0 CB A:ALA815 4.5 95.5 1.0 CA A:CYS864 4.6 0.3 1.0 CA A:CYS810 4.6 0.6 1.0 CB A:LYS812 4.6 0.6 1.0 CE2 A:TRP873 4.7 0.1 1.0 CA A:CYS869 4.9 0.1 1.0 N A:HIS871 4.9 0.9 1.0 N A:ALA815 5.0 95.8 1.0

F.Jiang, A.Ramanathan, M.T.Miller, G.Q.Tang, M.Gale, S.S.Patel, J.Marcotrigiano. Structural Basis of Rna Recognition and Activation By Innate Immune Receptor Rig-I. Nature V. 479 423 2011.
ISSN: ESSN 1476-4687
PubMed: 21947008
DOI: 10.1038/NATURE10537