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Atomistry » Zinc » PDB 5drr-5e9a » 5dy4 » |
Zinc in PDB 5dy4: Crystal Structure of Human SIRT2 in Complex with A Brominated 2ND Generation Sirreal Inhibitor and Nad+Protein crystallography data
The structure of Crystal Structure of Human SIRT2 in Complex with A Brominated 2ND Generation Sirreal Inhibitor and Nad+, PDB code: 5dy4
was solved by
T.Rumpf,
S.Gerhardt,
O.Einsle,
M.Jung,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5dy4:
The structure of Crystal Structure of Human SIRT2 in Complex with A Brominated 2ND Generation Sirreal Inhibitor and Nad+ also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of Human SIRT2 in Complex with A Brominated 2ND Generation Sirreal Inhibitor and Nad+
(pdb code 5dy4). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of Human SIRT2 in Complex with A Brominated 2ND Generation Sirreal Inhibitor and Nad+, PDB code: 5dy4: Zinc binding site 1 out of 1 in 5dy4Go back to![]() ![]()
Zinc binding site 1 out
of 1 in the Crystal Structure of Human SIRT2 in Complex with A Brominated 2ND Generation Sirreal Inhibitor and Nad+
![]() Mono view ![]() Stereo pair view
Reference:
M.Schiedel,
T.Rumpf,
B.Karaman,
A.Lehotzky,
J.Olah,
S.Gerhardt,
J.Ovadi,
W.Sippl,
O.Einsle,
M.Jung.
Aminothiazoles As Potent and Selective SIRT2 Inhibitors: A Structure-Activity Relationship Study. J.Med.Chem. V. 59 1599 2016.
Page generated: Sun Oct 27 14:55:48 2024
ISSN: ISSN 0022-2623 PubMed: 26696402 DOI: 10.1021/ACS.JMEDCHEM.5B01517 |
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