|
Atomistry » Zinc » PDB 4zw3-5a22 » 4zwx | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Zinc » PDB 4zw3-5a22 » 4zwx » |
Zinc in PDB 4zwx: Engineered Carbonic Anhydrase IX Mimic in Complex with Glucosyl Sulfamate InhibitorEnzymatic activity of Engineered Carbonic Anhydrase IX Mimic in Complex with Glucosyl Sulfamate Inhibitor
All present enzymatic activity of Engineered Carbonic Anhydrase IX Mimic in Complex with Glucosyl Sulfamate Inhibitor:
4.2.1.1; Protein crystallography data
The structure of Engineered Carbonic Anhydrase IX Mimic in Complex with Glucosyl Sulfamate Inhibitor, PDB code: 4zwx
was solved by
B.P.Mahon,
C.L.Lomelino,
A.L.Salguero,
R.Mckenna,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Zinc Binding Sites:
The binding sites of Zinc atom in the Engineered Carbonic Anhydrase IX Mimic in Complex with Glucosyl Sulfamate Inhibitor
(pdb code 4zwx). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Engineered Carbonic Anhydrase IX Mimic in Complex with Glucosyl Sulfamate Inhibitor, PDB code: 4zwx: Zinc binding site 1 out of 1 in 4zwxGo back to![]() ![]()
Zinc binding site 1 out
of 1 in the Engineered Carbonic Anhydrase IX Mimic in Complex with Glucosyl Sulfamate Inhibitor
![]() Mono view ![]() Stereo pair view
Reference:
B.P.Mahon,
C.L.Lomelino,
J.Ladwig,
G.M.Rankin,
J.M.Driscoll,
A.L.Salguero,
M.A.Pinard,
D.Vullo,
C.T.Supuran,
S.A.Poulsen,
R.Mckenna.
Mapping Selective Inhibition of the Cancer-Related Carbonic Anhydrase IX Using Structure-Activity Relationships of Glucosyl-Based Sulfamates. J.Med.Chem. V. 58 6630 2015.
Page generated: Sun Oct 27 12:06:51 2024
ISSN: ISSN 0022-2623 PubMed: 26203869 DOI: 10.1021/ACS.JMEDCHEM.5B00845 |
Last articlesFe in 2YXOFe in 2YRS Fe in 2YXC Fe in 2YNM Fe in 2YVJ Fe in 2YP1 Fe in 2YU2 Fe in 2YU1 Fe in 2YQB Fe in 2YOO |
© Copyright 2008-2020 by atomistry.com | ||
Home | Site Map | Copyright | Contact us | Privacy |