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Atomistry » Zinc » PDB 4xo5-4y8c » 4y86 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Zinc » PDB 4xo5-4y8c » 4y86 » |
Zinc in PDB 4y86: Crystal Structure of PDE9 in Complex with Racemic Inhibitor C33Enzymatic activity of Crystal Structure of PDE9 in Complex with Racemic Inhibitor C33
All present enzymatic activity of Crystal Structure of PDE9 in Complex with Racemic Inhibitor C33:
3.1.4.35; Protein crystallography data
The structure of Crystal Structure of PDE9 in Complex with Racemic Inhibitor C33, PDB code: 4y86
was solved by
M.Huang,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4y86:
The structure of Crystal Structure of PDE9 in Complex with Racemic Inhibitor C33 also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of PDE9 in Complex with Racemic Inhibitor C33
(pdb code 4y86). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of PDE9 in Complex with Racemic Inhibitor C33, PDB code: 4y86: Jump to Zinc binding site number: 1; 2; Zinc binding site 1 out of 2 in 4y86Go back to![]() ![]()
Zinc binding site 1 out
of 2 in the Crystal Structure of PDE9 in Complex with Racemic Inhibitor C33
![]() Mono view ![]() Stereo pair view
Zinc binding site 2 out of 2 in 4y86Go back to![]() ![]()
Zinc binding site 2 out
of 2 in the Crystal Structure of PDE9 in Complex with Racemic Inhibitor C33
![]() Mono view ![]() Stereo pair view
Reference:
M.Huang,
Y.Shao,
J.Hou,
W.Cui,
B.Liang,
Y.Huang,
Z.Li,
Y.Wu,
X.Zhu,
P.Liu,
Y.Wan,
H.Ke,
H.B.Luo.
Structural Asymmetry of Phosphodiesterase-9A and A Unique Pocket For Selective Binding of A Potent Enantiomeric Inhibitor. Mol.Pharmacol. V. 88 836 2015.
Page generated: Sun Oct 27 10:58:53 2024
ISSN: ESSN 1521-0111 PubMed: 26316540 DOI: 10.1124/MOL.115.099747 |
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