Zinc in PDB 4tzb: Structure of Ndm-Metallo-Beta-Lactamase

The structure of Structure of Ndm-Metallo-Beta-Lactamase, PDB code: 4tzb was solved by J.A.Ferguson, A.Makena, J.Brem, M.A.Mcdonough, C.J.Schofield, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	46.05 / 2.03
Space group	I 4 2 2
Cell size a, b, c (Å), α, β, γ (°)	120.244, 120.244, 89.192, 90.00, 90.00, 90.00
R / Rfree (%)	17.7 / 20.6

The structure of Structure of Ndm-Metallo-Beta-Lactamase also contains other interesting chemical elements:

Nickel	(Ni)	4 atoms
Cobalt	(Co)	1 atom
Cadmium	(Cd)	1 atom

The binding sites of Zinc atom in the Structure of Ndm-Metallo-Beta-Lactamase (pdb code 4tzb). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Structure of Ndm-Metallo-Beta-Lactamase, PDB code: 4tzb:

Zinc binding site 1 out of 1 in the Structure of Ndm-Metallo-Beta-Lactamase


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of Ndm-Metallo-Beta-Lactamase within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn301 b:29.6 occ:1.00 ND1 A:HIS122 2.0 28.3 1.0 NE2 A:HIS120 2.1 26.7 1.0 NE2 A:HIS189 2.1 28.5 1.0 O A:HOH416 2.1 32.2 1.0 CG A:HIS122 2.9 28.7 1.0 CD2 A:HIS189 3.0 27.6 1.0 CE1 A:HIS120 3.0 27.0 1.0 CE1 A:HIS122 3.0 28.3 1.0 CD2 A:HIS120 3.1 26.8 1.0 CE1 A:HIS189 3.1 27.8 1.0 CB A:HIS122 3.2 27.7 1.0 O A:HOH504 3.4 52.0 1.0 CD A:CD304 3.6 31.8 1.0 SG A:CYS208 3.9 31.6 1.0 OD1 A:ASP124 4.0 31.5 1.0 CD2 A:HIS122 4.1 28.8 1.0 NE2 A:HIS122 4.1 29.7 1.0 ND1 A:HIS120 4.1 26.8 1.0 CG A:HIS189 4.1 27.3 1.0 CG A:HIS120 4.2 26.4 1.0 CB A:CYS208 4.2 29.6 1.0 ND1 A:HIS189 4.2 27.2 1.0 CG2 A:THR190 4.5 25.2 1.0 O A:HOH521 4.6 24.8 1.0 CA A:HIS122 4.7 27.0 1.0 OD2 A:ASP124 4.8 33.1 1.0 CG A:ASP124 4.8 32.0 1.0 O A:HOH537 4.9 52.9 1.0

J.A.Ferguson, A.Makena, J.Brem, M.A.Mcdonough, C.J.Schofield. Structure of Metallo-Beta-Lactamase To Be Published.