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Atomistry » Zinc » PDB 4q47-4q8w » 4q8p » |
Zinc in PDB 4q8p: Trna-Guanine Transglycosylase (Tgt) Mutant V262D in Complex with 6- Amino-2-{[2-(Morpholin-4-Yl)Ethyl]Amino}-1H,7H,8H-Imidazo[4,5- G]Quinazolin-8-OneEnzymatic activity of Trna-Guanine Transglycosylase (Tgt) Mutant V262D in Complex with 6- Amino-2-{[2-(Morpholin-4-Yl)Ethyl]Amino}-1H,7H,8H-Imidazo[4,5- G]Quinazolin-8-One
All present enzymatic activity of Trna-Guanine Transglycosylase (Tgt) Mutant V262D in Complex with 6- Amino-2-{[2-(Morpholin-4-Yl)Ethyl]Amino}-1H,7H,8H-Imidazo[4,5- G]Quinazolin-8-One:
2.4.2.29; Protein crystallography data
The structure of Trna-Guanine Transglycosylase (Tgt) Mutant V262D in Complex with 6- Amino-2-{[2-(Morpholin-4-Yl)Ethyl]Amino}-1H,7H,8H-Imidazo[4,5- G]Quinazolin-8-One, PDB code: 4q8p
was solved by
M.Neeb,
A.Heine,
G.Klebe,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Zinc Binding Sites:
The binding sites of Zinc atom in the Trna-Guanine Transglycosylase (Tgt) Mutant V262D in Complex with 6- Amino-2-{[2-(Morpholin-4-Yl)Ethyl]Amino}-1H,7H,8H-Imidazo[4,5- G]Quinazolin-8-One
(pdb code 4q8p). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Trna-Guanine Transglycosylase (Tgt) Mutant V262D in Complex with 6- Amino-2-{[2-(Morpholin-4-Yl)Ethyl]Amino}-1H,7H,8H-Imidazo[4,5- G]Quinazolin-8-One, PDB code: 4q8p: Zinc binding site 1 out of 1 in 4q8pGo back to![]() ![]()
Zinc binding site 1 out
of 1 in the Trna-Guanine Transglycosylase (Tgt) Mutant V262D in Complex with 6- Amino-2-{[2-(Morpholin-4-Yl)Ethyl]Amino}-1H,7H,8H-Imidazo[4,5- G]Quinazolin-8-One
![]() Mono view ![]() Stereo pair view
Reference:
M.Neeb,
A.Heine,
G.Klebe.
Creating A Resistance Model For Tgt: the Effect of Mutations on Flexible Lin-Benzoguanine Substituents To Be Published.
Page generated: Sun Oct 27 06:21:44 2024
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