Zinc in PDB 4l5o: Crystal Structure of 26 kDa Gst D26H Mutant of Clonorchis Sinensis

The structure of Crystal Structure of 26 kDa Gst D26H Mutant of Clonorchis Sinensis, PDB code: 4l5o was solved by Y.J.Chung, Y.H.Han, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	59.57 / 2.09
Space group	P 31 2 1
Cell size a, b, c (Å), α, β, γ (°)	98.370, 98.370, 178.501, 90.00, 90.00, 120.00
R / Rfree (%)	20.2 / 24.8

The binding sites of Zinc atom in the Crystal Structure of 26 kDa Gst D26H Mutant of Clonorchis Sinensis (pdb code 4l5o). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of 26 kDa Gst D26H Mutant of Clonorchis Sinensis, PDB code: 4l5o:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of 26 kDa Gst D26H Mutant of Clonorchis Sinensis


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of 26 kDa Gst D26H Mutant of Clonorchis Sinensis within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn303 b:33.0 occ:1.00 NE2 A:HIS26 1.9 39.2 1.0 NE2 C:HIS26 2.0 31.8 1.0 NE2 A:HIS79 2.0 41.8 1.0 NE2 C:HIS79 2.1 31.5 1.0 CE1 A:HIS79 2.5 37.7 1.0 CE1 A:HIS26 2.8 40.2 1.0 CD2 C:HIS26 2.8 34.2 1.0 CD2 C:HIS79 3.0 32.3 1.0 CE1 C:HIS79 3.0 29.4 1.0 CD2 A:HIS26 3.0 39.7 1.0 CE1 C:HIS26 3.0 33.4 1.0 CD2 A:HIS79 3.2 38.0 1.0 ND1 A:HIS79 3.7 38.2 1.0 ND1 A:HIS26 3.9 41.0 1.0 ND1 C:HIS79 4.0 31.4 1.0 CG A:HIS79 4.0 36.2 1.0 CG C:HIS79 4.0 30.6 1.0 CG C:HIS26 4.0 31.4 1.0 CG A:HIS26 4.1 34.4 1.0 ND1 C:HIS26 4.1 31.0 1.0 O C:VAL24 4.9 31.5 1.0 O C:LYS78 5.0 27.5 1.0 O A:VAL24 5.0 30.4 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of 26 kDa Gst D26H Mutant of Clonorchis Sinensis


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of 26 kDa Gst D26H Mutant of Clonorchis Sinensis within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn303 b:74.2 occ:1.00 NE2 B:HIS79 2.2 40.0 1.0 ND1 B:HIS26 3.0 44.9 1.0 CE1 B:HIS79 3.1 40.4 1.0 CD2 B:HIS79 3.1 36.9 1.0 CE1 B:HIS26 3.2 30.8 1.0 ND1 B:HIS79 4.2 39.1 1.0 CG B:HIS79 4.3 36.0 1.0 CG B:HIS26 4.3 54.3 1.0 O B:VAL24 4.4 40.4 1.0 NE2 B:HIS26 4.5 44.9 1.0 CG2 B:VAL24 4.7 38.9 1.0 CB B:VAL24 4.8 38.1 1.0 N B:HIS26 5.0 53.3 1.0

Y.H.Han, S.J.Hong, H.K.Cheong, Y.J.Chung. Crystal Structures of 26KDA Clonorchis Sinensis Glutathione S-Transferase Reveal Zinc Binding and Putative Metal Binding. Biochem.Biophys.Res.Commun. 2013.
ISSN: ESSN 1090-2104
PubMed: 23916611
DOI: 10.1016/J.BBRC.2013.07.102