Zinc in PDB 4hkr: Calcium Release-Activated Calcium (Crac) Channel Orai

The structure of Calcium Release-Activated Calcium (Crac) Channel Orai, PDB code: 4hkr was solved by S.B.Long, X.Hou, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	19.93 / 3.35
Space group	P 21 3
Cell size a, b, c (Å), α, β, γ (°)	117.910, 117.910, 117.910, 90.00, 90.00, 90.00
R / Rfree (%)	27.8 / 27.9

The structure of Calcium Release-Activated Calcium (Crac) Channel Orai also contains other interesting chemical elements:

Barium	(Ba)	1 atom
Iron	(Fe)	2 atoms

The binding sites of Zinc atom in the Calcium Release-Activated Calcium (Crac) Channel Orai (pdb code 4hkr). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Calcium Release-Activated Calcium (Crac) Channel Orai, PDB code: 4hkr:

Zinc binding site 1 out of 1 in the Calcium Release-Activated Calcium (Crac) Channel Orai


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Calcium Release-Activated Calcium (Crac) Channel Orai within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn402 b:0.5 occ:0.33 NE2 A:HIS330 2.6 0.0 1.0 NE2 A:HIS334 3.0 0.1 1.0 CD2 A:HIS330 3.6 1.0 1.0 CE1 A:HIS330 3.6 0.8 1.0 CE1 A:HIS334 3.9 0.3 1.0 CD2 A:HIS334 4.0 0.5 1.0 ND1 A:HIS330 4.7 0.9 1.0 CG A:HIS330 4.7 0.6 1.0

X.Hou, L.Pedi, M.M.Diver, S.B.Long. Crystal Structure of the Calcium Release-Activated Calcium Channel Orai. Science V. 338 1308 2012.
ISSN: ISSN 0036-8075
PubMed: 23180775
DOI: 10.1126/SCIENCE.1228757