Atomistry » Zinc » PDB 4cz1-4d9q » 4d1v
Atomistry »
  Zinc »
    PDB 4cz1-4d9q »
      4d1v »

Zinc in PDB 4d1v: A F218Y Mutant of Vim-7 From Pseudomonas Aeruginosa

Protein crystallography data

The structure of A F218Y Mutant of Vim-7 From Pseudomonas Aeruginosa, PDB code: 4d1v was solved by H.-K.S.Leiros, S.Skagseth, K.S.W.Edvardsen, M.S.Lorentzen, G.E.K.Bjerga, I.Leiros, O.Samuelsen, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 24.730 / 1.70
Space group P 43
Cell size a, b, c (Å), α, β, γ (°) 69.947, 69.947, 46.936, 90.00, 90.00, 90.00
R / Rfree (%) 15.93 / 19.65

Zinc Binding Sites:

The binding sites of Zinc atom in the A F218Y Mutant of Vim-7 From Pseudomonas Aeruginosa (pdb code 4d1v). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the A F218Y Mutant of Vim-7 From Pseudomonas Aeruginosa, PDB code: 4d1v:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in 4d1v

Go back to Zinc Binding Sites List in 4d1v
Zinc binding site 1 out of 2 in the A F218Y Mutant of Vim-7 From Pseudomonas Aeruginosa


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of A F218Y Mutant of Vim-7 From Pseudomonas Aeruginosa within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn1292

b:20.1
occ:1.00
ND1 A:HIS118 2.0 19.6 1.0
NE2 A:HIS196 2.0 17.8 1.0
NE2 A:HIS116 2.1 14.7 1.0
O A:HOH2102 2.1 24.6 1.0
HB2 A:HIS118 2.9 21.4 1.0
CE1 A:HIS118 3.0 21.2 1.0
O A:HOH2103 3.0 31.6 1.0
CE1 A:HIS116 3.0 16.6 1.0
CE1 A:HIS196 3.0 25.4 1.0
CG A:HIS118 3.0 20.2 1.0
CD2 A:HIS196 3.0 16.2 1.0
CD2 A:HIS116 3.0 15.1 1.0
HE1 A:HIS118 3.1 25.5 1.0
HE1 A:HIS116 3.2 19.9 1.0
HE1 A:HIS196 3.2 30.4 1.0
HD2 A:HIS196 3.2 19.4 1.0
HD2 A:HIS116 3.2 18.1 1.0
CB A:HIS118 3.4 17.8 1.0
HB3 A:HIS118 3.6 21.4 1.0
ZN A:ZN1293 3.7 30.4 1.0
OD1 A:ASP120 4.0 21.7 1.0
HB2 A:CYS221 4.0 23.5 1.0
O A:HOH2182 4.0 35.5 1.0
NE2 A:HIS118 4.1 21.6 1.0
ND1 A:HIS116 4.1 14.0 1.0
ND1 A:HIS196 4.1 18.4 1.0
CD2 A:HIS118 4.1 20.8 1.0
CG A:HIS196 4.2 17.7 1.0
CG A:HIS116 4.2 15.4 1.0
HB3 A:CYS221 4.3 23.5 1.0
CB A:CYS221 4.4 19.6 1.0
SG A:CYS221 4.5 24.0 1.0
H A:HIS118 4.5 17.1 1.0
OD2 A:ASP120 4.5 19.9 1.0
O A:HOH2109 4.5 34.9 1.0
CG A:ASP120 4.7 18.8 1.0
HD21 A:ASN233 4.7 45.9 1.0
CA A:HIS118 4.8 14.8 1.0
HB3 A:SER197 4.8 21.2 1.0
HG2 A:ARG121 4.8 16.4 1.0
HE2 A:HIS118 4.9 25.9 1.0
HD1 A:HIS116 4.9 16.8 1.0
HD1 A:HIS196 4.9 22.1 1.0
HE A:ARG121 4.9 19.3 1.0
HD2 A:HIS118 5.0 25.0 1.0

Zinc binding site 2 out of 2 in 4d1v

Go back to Zinc Binding Sites List in 4d1v
Zinc binding site 2 out of 2 in the A F218Y Mutant of Vim-7 From Pseudomonas Aeruginosa


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of A F218Y Mutant of Vim-7 From Pseudomonas Aeruginosa within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn1293

b:30.4
occ:1.00
NE2 A:HIS263 2.1 20.4 1.0
OD2 A:ASP120 2.1 19.9 1.0
O A:HOH2182 2.2 35.5 1.0
O A:HOH2102 2.3 24.6 1.0
SG A:CYS221 2.4 24.0 1.0
HH21 A:ARG121 3.0 26.6 1.0
CE1 A:HIS263 3.1 19.5 1.0
CD2 A:HIS263 3.1 22.6 1.0
CG A:ASP120 3.2 18.8 1.0
HD2 A:HIS263 3.3 27.1 1.0
HE1 A:HIS263 3.3 23.4 1.0
HB3 A:CYS221 3.3 23.5 1.0
HE1 A:HIS116 3.5 19.9 1.0
CB A:CYS221 3.5 19.6 1.0
HE A:ARG121 3.5 19.3 1.0
O A:HOH2109 3.6 34.9 1.0
OD1 A:ASP120 3.6 21.7 1.0
ZN A:ZN1292 3.7 20.1 1.0
NH2 A:ARG121 3.8 22.1 1.0
HB2 A:CYS221 3.9 23.5 1.0
O A:HOH2103 3.9 31.6 1.0
ND1 A:HIS263 4.2 18.1 1.0
CE1 A:HIS116 4.2 16.6 1.0
NE A:ARG121 4.2 16.1 1.0
CG A:HIS263 4.2 18.3 1.0
O A:HOH2181 4.3 36.5 1.0
NE2 A:HIS196 4.4 17.8 1.0
HH22 A:ARG121 4.4 26.6 1.0
HE1 A:HIS196 4.4 30.4 1.0
NE2 A:HIS116 4.4 14.7 1.0
CB A:ASP120 4.5 16.6 1.0
CZ A:ARG121 4.5 19.6 1.0
O A:HOH2056 4.5 43.3 1.0
CE1 A:HIS196 4.5 25.4 1.0
HB2 A:ASP120 4.6 19.9 1.0
HA3 A:GLY262 4.7 17.6 1.0
HB3 A:ASP120 4.7 19.9 1.0
HA A:CYS221 4.7 20.3 1.0
CA A:CYS221 4.8 16.9 1.0
HG2 A:ARG121 4.9 16.4 1.0
HD1 A:HIS263 5.0 21.8 1.0

Reference:

H.-K.S.Leiros, S.Skagseth, K.S.W.Edvardsen, M.S.Lorentzen, G.E.K.Bjerga, I.Leiros, O.Samuelsen. HIS224 Alters the R2 Drug Binding Site and PHE218 Influences the Catalytic Efficiency in the Metallo-Beta-Lactamase Vim-7. Antimicrob.Agents Chemother. V. 58 4826 2014.
ISSN: ISSN 0066-4804
PubMed: 24913158
DOI: 10.1128/AAC.02735-13
Page generated: Sat Oct 26 21:16:55 2024

Last articles

Zn in 9MJ5
Zn in 9HNW
Zn in 9G0L
Zn in 9FNE
Zn in 9DZN
Zn in 9E0I
Zn in 9D32
Zn in 9DAK
Zn in 8ZXC
Zn in 8ZUF
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy