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Atomistry » Zinc » PDB 4csz-4cyk » 4cx0 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Zinc » PDB 4csz-4cyk » 4cx0 » |
Zinc in PDB 4cx0: Structure of Bovine Endothelial Nitric Oxide Synthase Y477A Mutant Heme Domain in Complex with 6-((((3S, 5R)-5-(((6- Amino-4-Methylpyridin-2-Yl)Methoxy)Methyl)Pyrrolidin-3-Yl) Oxy)Methyl)-4-Methylpyridin-2-AmineEnzymatic activity of Structure of Bovine Endothelial Nitric Oxide Synthase Y477A Mutant Heme Domain in Complex with 6-((((3S, 5R)-5-(((6- Amino-4-Methylpyridin-2-Yl)Methoxy)Methyl)Pyrrolidin-3-Yl) Oxy)Methyl)-4-Methylpyridin-2-Amine
All present enzymatic activity of Structure of Bovine Endothelial Nitric Oxide Synthase Y477A Mutant Heme Domain in Complex with 6-((((3S, 5R)-5-(((6- Amino-4-Methylpyridin-2-Yl)Methoxy)Methyl)Pyrrolidin-3-Yl) Oxy)Methyl)-4-Methylpyridin-2-Amine:
1.14.13.39; Protein crystallography data
The structure of Structure of Bovine Endothelial Nitric Oxide Synthase Y477A Mutant Heme Domain in Complex with 6-((((3S, 5R)-5-(((6- Amino-4-Methylpyridin-2-Yl)Methoxy)Methyl)Pyrrolidin-3-Yl) Oxy)Methyl)-4-Methylpyridin-2-Amine, PDB code: 4cx0
was solved by
H.Li,
T.L.Poulos,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4cx0:
The structure of Structure of Bovine Endothelial Nitric Oxide Synthase Y477A Mutant Heme Domain in Complex with 6-((((3S, 5R)-5-(((6- Amino-4-Methylpyridin-2-Yl)Methoxy)Methyl)Pyrrolidin-3-Yl) Oxy)Methyl)-4-Methylpyridin-2-Amine also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Structure of Bovine Endothelial Nitric Oxide Synthase Y477A Mutant Heme Domain in Complex with 6-((((3S, 5R)-5-(((6- Amino-4-Methylpyridin-2-Yl)Methoxy)Methyl)Pyrrolidin-3-Yl) Oxy)Methyl)-4-Methylpyridin-2-Amine
(pdb code 4cx0). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Structure of Bovine Endothelial Nitric Oxide Synthase Y477A Mutant Heme Domain in Complex with 6-((((3S, 5R)-5-(((6- Amino-4-Methylpyridin-2-Yl)Methoxy)Methyl)Pyrrolidin-3-Yl) Oxy)Methyl)-4-Methylpyridin-2-Amine, PDB code: 4cx0: Zinc binding site 1 out of 1 in 4cx0Go back to![]() ![]()
Zinc binding site 1 out
of 1 in the Structure of Bovine Endothelial Nitric Oxide Synthase Y477A Mutant Heme Domain in Complex with 6-((((3S, 5R)-5-(((6- Amino-4-Methylpyridin-2-Yl)Methoxy)Methyl)Pyrrolidin-3-Yl) Oxy)Methyl)-4-Methylpyridin-2-Amine
![]() Mono view ![]() Stereo pair view
Reference:
H.Li,
J.Jamal,
S.L.Delker,
C.Plaza,
H.Ji,
Q.Jing,
H.Huang,
S.Kang,
R.B.Silverman,
T.L.Poulos.
Mobility of A Conserved Tyrosine Residue Controls Isoform- Dependent Enzyme-Inhibitor Interactions in Nitric Oxide Synthases. Biochemistry V. 53 5272 2014.
Page generated: Sat Oct 26 21:09:50 2024
ISSN: ISSN 0006-2960 PubMed: 25089924 DOI: 10.1021/BI500561H |
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