Zinc in PDB 3zvz: Phd Finger of Human UHRF1

The structure of Phd Finger of Human UHRF1, PDB code: 3zvz was solved by N.Lallous, C.Birck, A.G.Mc Ewen, P.Legrand, J.P.Samama, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	24.394 / 1.44
Space group	P 65 2 2
Cell size a, b, c (Å), α, β, γ (°)	51.006, 51.006, 83.629, 90.00, 90.00, 120.00
R / Rfree (%)	16.9 / 19.72

The binding sites of Zinc atom in the Phd Finger of Human UHRF1 (pdb code 3zvz). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Phd Finger of Human UHRF1, PDB code: 3zvz:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Phd Finger of Human UHRF1


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Phd Finger of Human UHRF1 within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn433 b:24.8 occ:1.00 ND1 B:HIS341 2.1 23.1 1.0 SG B:CYS344 2.3 27.5 1.0 SG B:CYS321 2.3 24.4 1.0 SG B:CYS318 2.3 22.7 1.0 CB B:CYS318 3.0 21.5 1.0 CE1 B:HIS341 3.1 23.5 1.0 CG B:HIS341 3.1 20.4 1.0 CB B:CYS321 3.2 24.4 1.0 CB B:CYS344 3.3 28.9 1.0 CB B:HIS341 3.5 21.6 1.0 N B:CYS321 3.8 25.9 1.0 CA B:CYS321 4.1 24.9 1.0 N B:HIS341 4.1 20.1 1.0 NE2 B:HIS341 4.2 22.6 1.0 CD2 B:HIS341 4.3 20.5 1.0 CA B:HIS341 4.4 22.0 1.0 CA B:CYS318 4.5 20.3 1.0 CE1 B:TYR343 4.6 30.5 1.0 CA B:CYS344 4.7 28.8 1.0 CB B:LEU320 4.8 30.3 1.0 C B:LEU320 4.8 28.8 1.0 O B:HOH2030 4.8 58.8 1.0 C B:CYS321 4.9 25.7 1.0 NE2 B:GLN325 4.9 36.7 1.0 N B:GLY322 5.0 24.0 1.0

Zinc binding site 2 out of 2 in the Phd Finger of Human UHRF1


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Phd Finger of Human UHRF1 within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn434 b:30.9 occ:1.00 SG B:CYS363 2.3 34.8 1.0 SG B:CYS333 2.3 25.0 1.0 SG B:CYS336 2.3 31.8 1.0 SG B:CYS360 2.4 27.9 1.0 CB B:CYS333 3.2 25.9 1.0 CB B:CYS363 3.2 36.1 1.0 CB B:CYS336 3.3 33.8 1.0 CB B:CYS360 3.4 25.8 1.0 N B:CYS336 3.7 26.3 1.0 N B:CYS360 4.0 23.9 1.0 CA B:CYS336 4.1 29.4 1.0 N B:CYS363 4.1 36.3 1.0 CA B:CYS360 4.2 26.4 1.0 CA B:CYS363 4.3 36.2 1.0 CE B:MET338 4.5 37.6 0.5 CA B:CYS333 4.6 23.2 1.0 CB B:GLU335 4.7 31.1 1.0 C B:GLU335 4.8 27.4 1.0 C B:CYS360 4.8 30.9 1.0 C B:CYS336 4.9 27.6 1.0 O B:CYS360 4.9 30.0 1.0 CE1 B:PHE340 5.0 24.6 1.0

N.Lallous, P.Legrand, A.G.Mcewen, S.Ramon-Maiques, J.P.Samama, C.Birck. The Phd Finger of Human UHRF1 Reveals A New Subgroup of Unmethylated Histone H3 Tail Readers. Plos One V. 6E27599 2011.
ISSN: ISSN 1932-6203
PubMed: 22096602
DOI: 10.1371/JOURNAL.PONE.0027599