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Atomistry » Zinc » PDB 3v3f-3vh3 » 3vbd | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Zinc » PDB 3v3f-3vh3 » 3vbd » |
Zinc in PDB 3vbd: Complex of Human Carbonic Anhydrase II with 4-(6-Methoxy-3,4- Dihydroisoquinolin-1-Yl)BenzenesulfonamideEnzymatic activity of Complex of Human Carbonic Anhydrase II with 4-(6-Methoxy-3,4- Dihydroisoquinolin-1-Yl)Benzenesulfonamide
All present enzymatic activity of Complex of Human Carbonic Anhydrase II with 4-(6-Methoxy-3,4- Dihydroisoquinolin-1-Yl)Benzenesulfonamide:
4.2.1.1; Protein crystallography data
The structure of Complex of Human Carbonic Anhydrase II with 4-(6-Methoxy-3,4- Dihydroisoquinolin-1-Yl)Benzenesulfonamide, PDB code: 3vbd
was solved by
P.Mader,
J.Brynda,
P.Rezacova,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 3vbd:
The structure of Complex of Human Carbonic Anhydrase II with 4-(6-Methoxy-3,4- Dihydroisoquinolin-1-Yl)Benzenesulfonamide also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Complex of Human Carbonic Anhydrase II with 4-(6-Methoxy-3,4- Dihydroisoquinolin-1-Yl)Benzenesulfonamide
(pdb code 3vbd). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Complex of Human Carbonic Anhydrase II with 4-(6-Methoxy-3,4- Dihydroisoquinolin-1-Yl)Benzenesulfonamide, PDB code: 3vbd: Zinc binding site 1 out of 1 in 3vbdGo back to![]() ![]()
Zinc binding site 1 out
of 1 in the Complex of Human Carbonic Anhydrase II with 4-(6-Methoxy-3,4- Dihydroisoquinolin-1-Yl)Benzenesulfonamide
![]() Mono view ![]() Stereo pair view
Reference:
R.Gitto,
F.M.Damiano,
P.Mader,
L.De Luca,
S.Ferro,
C.T.Supuran,
D.Vullo,
J.Brynda,
P.Rezacova,
A.Chimirri.
Synthesis, Structure-Activity Relationship Studies, and X-Ray Crystallographic Analysis of Arylsulfonamides As Potent Carbonic Anhydrase Inhibitors. J.Med.Chem. V. 55 3891 2012.
Page generated: Sat Oct 26 17:39:54 2024
ISSN: ISSN 0022-2623 PubMed: 22443141 DOI: 10.1021/JM300112W |
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