Zinc in PDB 3tp2: Crystal Structure of the Splicing Factor CWC2 From Yeast

The structure of Crystal Structure of the Splicing Factor CWC2 From Yeast, PDB code: 3tp2 was solved by J.Schmitzova, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	47.26 / 2.40
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	58.700, 79.700, 113.800, 90.00, 90.00, 90.00
R / Rfree (%)	22.1 / 25.6

The structure of Crystal Structure of the Splicing Factor CWC2 From Yeast also contains other interesting chemical elements:

Sodium

(Na)

2 atoms

The binding sites of Zinc atom in the Crystal Structure of the Splicing Factor CWC2 From Yeast (pdb code 3tp2). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of the Splicing Factor CWC2 From Yeast, PDB code: 3tp2:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of the Splicing Factor CWC2 From Yeast


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of the Splicing Factor CWC2 From Yeast within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn229 b:17.2 occ:1.00 NE2 A:HIS91 2.1 16.5 1.0 SG A:CYS81 2.3 18.3 1.0 SG A:CYS73 2.3 16.8 1.0 SG A:CYS87 2.3 23.0 1.0 CE1 A:HIS91 2.9 16.5 1.0 CB A:CYS73 3.1 17.0 1.0 CD2 A:HIS91 3.2 16.5 1.0 CB A:CYS87 3.3 24.4 1.0 CB A:CYS81 3.3 18.6 1.0 ND1 A:HIS91 4.1 16.5 1.0 CG A:HIS91 4.2 16.3 1.0 CB A:PHE76 4.4 13.6 1.0 N A:PHE76 4.5 13.2 1.0 CA A:CYS73 4.6 16.3 1.0 O A:HOH265 4.6 15.9 1.0 CA A:CYS81 4.7 19.1 1.0 CA A:CYS87 4.7 25.8 1.0 CB A:LEU83 4.8 25.4 1.0 CB A:PHE75 4.8 14.2 1.0 O A:TYR89 4.9 20.7 1.0 CA A:PHE76 5.0 13.3 1.0 CD1 A:LEU83 5.0 25.9 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of the Splicing Factor CWC2 From Yeast


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of the Splicing Factor CWC2 From Yeast within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn229 b:18.6 occ:1.00 NE2 B:HIS91 2.1 18.1 1.0 SG B:CYS87 2.2 20.1 1.0 SG B:CYS81 2.3 18.8 1.0 SG B:CYS73 2.3 14.8 1.0 CE1 B:HIS91 2.9 17.1 1.0 CB B:CYS73 3.1 15.3 1.0 CB B:CYS87 3.1 22.3 1.0 CD2 B:HIS91 3.2 17.1 1.0 CB B:CYS81 3.4 19.6 1.0 ND1 B:HIS91 4.1 16.3 1.0 CG B:HIS91 4.3 17.0 1.0 CB B:PHE76 4.4 15.1 1.0 CA B:CYS87 4.5 23.7 1.0 CA B:CYS73 4.6 14.7 1.0 N B:PHE76 4.6 14.9 1.0 CA B:CYS81 4.7 20.4 1.0 CB B:PHE75 4.9 16.2 1.0 CB B:LEU83 4.9 26.1 1.0

J.Schmitzova, N.Rasche, O.Dybkov, K.Kramer, P.Fabrizio, H.Urlaub, R.Luhrmann, V.Pena. Crystal Structure of CWC2 Reveals A Novel Architecture of A Multipartite Rna-Binding Protein. Embo J. V. 31 2222 2012.
ISSN: ISSN 0261-4189
PubMed: 22407296
DOI: 10.1038/EMBOJ.2012.58