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Atomistry » Zinc » PDB 3sck-3sjd » 3sfx » |
Zinc in PDB 3sfx: Cryptococcus Neoformans Protein Farnesyltransferase in Complex with Fpt-II and TipifarnibProtein crystallography data
The structure of Cryptococcus Neoformans Protein Farnesyltransferase in Complex with Fpt-II and Tipifarnib, PDB code: 3sfx
was solved by
M.A.Hast,
L.S.Beese,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 3sfx:
The structure of Cryptococcus Neoformans Protein Farnesyltransferase in Complex with Fpt-II and Tipifarnib also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Cryptococcus Neoformans Protein Farnesyltransferase in Complex with Fpt-II and Tipifarnib
(pdb code 3sfx). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Cryptococcus Neoformans Protein Farnesyltransferase in Complex with Fpt-II and Tipifarnib, PDB code: 3sfx: Zinc binding site 1 out of 1 in 3sfxGo back to![]() ![]()
Zinc binding site 1 out
of 1 in the Cryptococcus Neoformans Protein Farnesyltransferase in Complex with Fpt-II and Tipifarnib
![]() Mono view ![]() Stereo pair view
Reference:
M.A.Hast,
C.B.Nichols,
S.M.Armstrong,
S.M.Kelly,
H.W.Hellinga,
J.A.Alspaugh,
L.S.Beese.
Structures of Cryptococcus Neoformans Protein Farnesyltransferase Reveal Strategies For Developing Inhibitors That Target Fungal Pathogens. J.Biol.Chem. V. 286 35149 2011.
Page generated: Sat Oct 26 15:44:38 2024
ISSN: ISSN 0021-9258 PubMed: 21816822 DOI: 10.1074/JBC.M111.250506 |
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