Atomistry » Zinc » PDB 3oxk-3p44 » 3p2x
Atomistry »
  Zinc »
    PDB 3oxk-3p44 »
      3p2x »

Zinc in PDB 3p2x: Insulin Fibrillation Is the Janus Face of Induced Fit. A Chiaral Clamp Stabilizes the Native State at the Expense of Activity

Protein crystallography data

The structure of Insulin Fibrillation Is the Janus Face of Induced Fit. A Chiaral Clamp Stabilizes the Native State at the Expense of Activity, PDB code: 3p2x was solved by Q.X.Hua, Z.L.Wan, K.Huang, S.Q.Hu, N.F.Phillip, W.H.Jia, J.Whittingham, G.G.Dodson, P.G.Katsoyannis, M.A.Weiss, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 32.38 / 2.00
Space group H 3
Cell size a, b, c (Å), α, β, γ (°) 78.363, 78.363, 36.848, 90.00, 90.00, 120.00
R / Rfree (%) 22.9 / 31.4

Other elements in 3p2x:

The structure of Insulin Fibrillation Is the Janus Face of Induced Fit. A Chiaral Clamp Stabilizes the Native State at the Expense of Activity also contains other interesting chemical elements:

Chlorine (Cl) 2 atoms

Zinc Binding Sites:

The binding sites of Zinc atom in the Insulin Fibrillation Is the Janus Face of Induced Fit. A Chiaral Clamp Stabilizes the Native State at the Expense of Activity (pdb code 3p2x). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Insulin Fibrillation Is the Janus Face of Induced Fit. A Chiaral Clamp Stabilizes the Native State at the Expense of Activity, PDB code: 3p2x:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in 3p2x

Go back to Zinc Binding Sites List in 3p2x
Zinc binding site 1 out of 2 in the Insulin Fibrillation Is the Janus Face of Induced Fit. A Chiaral Clamp Stabilizes the Native State at the Expense of Activity


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Insulin Fibrillation Is the Janus Face of Induced Fit. A Chiaral Clamp Stabilizes the Native State at the Expense of Activity within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Zn31

b:11.5
occ:0.33
NE2 B:HIS10 2.1 31.3 1.0
CL B:CL32 2.3 47.6 0.3
CE1 B:HIS10 3.0 31.6 1.0
CD2 B:HIS10 3.1 31.6 1.0
ND1 B:HIS10 4.2 32.4 1.0
CG B:HIS10 4.2 32.2 1.0

Zinc binding site 2 out of 2 in 3p2x

Go back to Zinc Binding Sites List in 3p2x
Zinc binding site 2 out of 2 in the Insulin Fibrillation Is the Janus Face of Induced Fit. A Chiaral Clamp Stabilizes the Native State at the Expense of Activity


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Insulin Fibrillation Is the Janus Face of Induced Fit. A Chiaral Clamp Stabilizes the Native State at the Expense of Activity within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Zn31

b:11.3
occ:0.33
NE2 D:HIS10 2.0 34.9 1.0
CL D:CL32 2.3 13.9 0.3
CE1 D:HIS10 3.0 36.8 1.0
CD2 D:HIS10 3.0 32.9 1.0
ND1 D:HIS10 4.1 31.6 1.0
CG D:HIS10 4.1 32.9 1.0
O D:LEU6 4.5 38.3 1.0
CB D:LEU6 4.6 39.0 1.0
O D:HOH38 5.0 46.6 1.0

Reference:

Q.X.Hua, Z.L.Wan, K.Huang, S.Q.Hu, N.F.Phillip, W.H.Jia, J.Whittingham, G.G.Dodson, P.G.Katsoyannis, M.A.Weiss. Insulin Fibrillation Is the Janus Face of Induced Fit. A Chiral Clamp Stabilizes the Native State at the Expense of Activity To Be Published.
Page generated: Sat Oct 26 11:17:31 2024

Last articles

Mg in 3CPW
Mg in 3CZJ
Mg in 3D19
Mg in 3CZ4
Mg in 3CZ1
Mg in 3CZ0
Mg in 3CXO
Mg in 3CYZ
Mg in 3CYI
Mg in 3CX8
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy