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Atomistry » Zinc » PDB 3oxk-3p44 » 3oy0 » |
Zinc in PDB 3oy0: Human Carbonic Anhydrase II Complexed with 1-(4-(4-(2- (Isopropylsulfonyl)Phenylamino)-1H-Pyrrolo[2,3-B]Pyridin-6-Ylamino)- 3-Methoxyphenyl)Piperidin-4-OlEnzymatic activity of Human Carbonic Anhydrase II Complexed with 1-(4-(4-(2- (Isopropylsulfonyl)Phenylamino)-1H-Pyrrolo[2,3-B]Pyridin-6-Ylamino)- 3-Methoxyphenyl)Piperidin-4-Ol
All present enzymatic activity of Human Carbonic Anhydrase II Complexed with 1-(4-(4-(2- (Isopropylsulfonyl)Phenylamino)-1H-Pyrrolo[2,3-B]Pyridin-6-Ylamino)- 3-Methoxyphenyl)Piperidin-4-Ol:
4.2.1.1; Protein crystallography data
The structure of Human Carbonic Anhydrase II Complexed with 1-(4-(4-(2- (Isopropylsulfonyl)Phenylamino)-1H-Pyrrolo[2,3-B]Pyridin-6-Ylamino)- 3-Methoxyphenyl)Piperidin-4-Ol, PDB code: 3oy0
was solved by
M.Aggarwal,
R.Mckenna,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Zinc Binding Sites:
The binding sites of Zinc atom in the Human Carbonic Anhydrase II Complexed with 1-(4-(4-(2- (Isopropylsulfonyl)Phenylamino)-1H-Pyrrolo[2,3-B]Pyridin-6-Ylamino)- 3-Methoxyphenyl)Piperidin-4-Ol
(pdb code 3oy0). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Human Carbonic Anhydrase II Complexed with 1-(4-(4-(2- (Isopropylsulfonyl)Phenylamino)-1H-Pyrrolo[2,3-B]Pyridin-6-Ylamino)- 3-Methoxyphenyl)Piperidin-4-Ol, PDB code: 3oy0: Zinc binding site 1 out of 1 in 3oy0Go back to![]() ![]()
Zinc binding site 1 out
of 1 in the Human Carbonic Anhydrase II Complexed with 1-(4-(4-(2- (Isopropylsulfonyl)Phenylamino)-1H-Pyrrolo[2,3-B]Pyridin-6-Ylamino)- 3-Methoxyphenyl)Piperidin-4-Ol
![]() Mono view ![]() Stereo pair view
Reference:
N.Hen,
M.Bialer,
B.Yagen,
A.Maresca,
M.Aggarwal,
A.H.Robbins,
R.Mckenna,
A.Scozzafava,
C.T.Supuran.
Anticonvulsant 4-Aminobenzenesulfonamide Derivatives with Branched-Alkylamide Moieties: X-Ray Crystallography and Inhibition Studies of Human Carbonic Anhydrase Isoforms I, II, VII, and Xiv. J.Med.Chem. V. 54 3977 2011.
Page generated: Sat Oct 26 11:10:41 2024
ISSN: ISSN 0022-2623 PubMed: 21506569 DOI: 10.1021/JM200209N |
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