Zinc in PDB 3ovl: Structure of An Amyloid Forming Peptide Vqivyk From the Tau Protein in Complex with Orange G

The structure of Structure of An Amyloid Forming Peptide Vqivyk From the Tau Protein in Complex with Orange G, PDB code: 3ovl was solved by M.Landau, D.Eisenberg, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	26.82 / 1.81
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	55.056, 4.831, 22.127, 90.00, 102.98, 90.00
R / Rfree (%)	25.9 / 25.9

The binding sites of Zinc atom in the Structure of An Amyloid Forming Peptide Vqivyk From the Tau Protein in Complex with Orange G (pdb code 3ovl). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Structure of An Amyloid Forming Peptide Vqivyk From the Tau Protein in Complex with Orange G, PDB code: 3ovl:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Structure of An Amyloid Forming Peptide Vqivyk From the Tau Protein in Complex with Orange G


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of An Amyloid Forming Peptide Vqivyk From the Tau Protein in Complex with Orange G within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn7 b:32.0 occ:0.50 O4 A:ORA79 2.3 29.5 0.2 NZ A:LYS6 2.7 25.8 1.0 C9 A:ORA79 2.8 30.7 0.2 C15 A:ORA79 2.8 31.5 0.2 S1 A:ORA79 2.9 32.1 0.2 CE A:LYS6 3.2 25.8 1.0 O3 A:ORA79 3.3 32.6 0.2 C16 A:ORA79 3.7 30.3 0.2 C8 A:ORA79 3.7 31.9 0.2 O5 A:ORA79 4.0 25.5 0.2 O1 A:ORA79 4.3 33.8 0.2 C11 A:ORA79 4.4 30.7 0.2 C10 A:ORA79 4.4 30.6 0.2 S2 A:ORA79 4.5 30.2 0.2 CD A:LYS6 4.7 22.6 1.0

Zinc binding site 2 out of 2 in the Structure of An Amyloid Forming Peptide Vqivyk From the Tau Protein in Complex with Orange G


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Structure of An Amyloid Forming Peptide Vqivyk From the Tau Protein in Complex with Orange G within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn8 b:22.2 occ:1.00 OXT A:ACY9 1.9 20.9 1.0 O A:LYS6 2.0 15.3 1.0 C A:ACY9 2.9 22.1 1.0 C A:LYS6 2.9 16.4 1.0 OXT A:LYS6 3.0 16.4 1.0 CH3 A:ACY9 3.3 23.4 1.0 O A:ACY9 4.0 22.0 1.0 O A:HOH10 4.1 28.9 1.0 CA A:LYS6 4.3 14.8 1.0 CB A:LYS6 4.9 16.1 1.0 O A:HOH11 5.0 27.8 1.0

M.Landau, M.R.Sawaya, K.F.Faull, A.Laganowsky, L.Jiang, S.A.Sievers, J.Liu, J.R.Barrio, D.Eisenberg. Towards A Pharmacophore For Amyloid. Plos Biol. V. 9 E1001 2011.
ISSN: ISSN 1544-9173
PubMed: 21695112
DOI: 10.1371/JOURNAL.PBIO.1001080