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Atomistry » Zinc » PDB 3nik-3nny » 3nln » |
Zinc in PDB 3nln: Structure of Neuronal Nitric Oxide Synthase R349A Mutant Heme Domain in Complex with 6-{{(3'R,4'S)-3'-[2"-(3'''-Fluorophenethylamino) Ethoxy]Pyrrolidin-4'-Yl}Methyl}-4-Methylpyridin-2-AmineEnzymatic activity of Structure of Neuronal Nitric Oxide Synthase R349A Mutant Heme Domain in Complex with 6-{{(3'R,4'S)-3'-[2"-(3'''-Fluorophenethylamino) Ethoxy]Pyrrolidin-4'-Yl}Methyl}-4-Methylpyridin-2-Amine
All present enzymatic activity of Structure of Neuronal Nitric Oxide Synthase R349A Mutant Heme Domain in Complex with 6-{{(3'R,4'S)-3'-[2"-(3'''-Fluorophenethylamino) Ethoxy]Pyrrolidin-4'-Yl}Methyl}-4-Methylpyridin-2-Amine:
1.14.13.39; Protein crystallography data
The structure of Structure of Neuronal Nitric Oxide Synthase R349A Mutant Heme Domain in Complex with 6-{{(3'R,4'S)-3'-[2"-(3'''-Fluorophenethylamino) Ethoxy]Pyrrolidin-4'-Yl}Methyl}-4-Methylpyridin-2-Amine, PDB code: 3nln
was solved by
H.Li,
S.L.Delker,
T.L.Poulos,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 3nln:
The structure of Structure of Neuronal Nitric Oxide Synthase R349A Mutant Heme Domain in Complex with 6-{{(3'R,4'S)-3'-[2"-(3'''-Fluorophenethylamino) Ethoxy]Pyrrolidin-4'-Yl}Methyl}-4-Methylpyridin-2-Amine also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Structure of Neuronal Nitric Oxide Synthase R349A Mutant Heme Domain in Complex with 6-{{(3'R,4'S)-3'-[2"-(3'''-Fluorophenethylamino) Ethoxy]Pyrrolidin-4'-Yl}Methyl}-4-Methylpyridin-2-Amine
(pdb code 3nln). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Structure of Neuronal Nitric Oxide Synthase R349A Mutant Heme Domain in Complex with 6-{{(3'R,4'S)-3'-[2"-(3'''-Fluorophenethylamino) Ethoxy]Pyrrolidin-4'-Yl}Methyl}-4-Methylpyridin-2-Amine, PDB code: 3nln: Zinc binding site 1 out of 1 in 3nlnGo back to![]() ![]()
Zinc binding site 1 out
of 1 in the Structure of Neuronal Nitric Oxide Synthase R349A Mutant Heme Domain in Complex with 6-{{(3'R,4'S)-3'-[2"-(3'''-Fluorophenethylamino) Ethoxy]Pyrrolidin-4'-Yl}Methyl}-4-Methylpyridin-2-Amine
![]() Mono view ![]() Stereo pair view
Reference:
H.Ji,
S.L.Delker,
H.Li,
P.Martasek,
L.J.Roman,
T.L.Poulos,
R.B.Silverman.
Exploration of the Active Site of Neuronal Nitric Oxide Synthase By the Design and Synthesis of Pyrrolidinomethyl 2-Aminopyridine Derivatives. J.Med.Chem. V. 53 7804 2010.
Page generated: Sat Oct 26 10:27:49 2024
ISSN: ISSN 0022-2623 PubMed: 20958055 DOI: 10.1021/JM100947X |
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