Zinc in PDB 3lrr: Crystal Structure of Human Rig-I Ctd Bound to A 12 Bp Au Rich 5' Ppp Dsrna

The structure of Crystal Structure of Human Rig-I Ctd Bound to A 12 Bp Au Rich 5' Ppp Dsrna, PDB code: 3lrr was solved by P.Li, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	30.19 / 2.15
Space group	P 65
Cell size a, b, c (Å), α, β, γ (°)	83.010, 83.010, 111.220, 90.00, 90.00, 120.00
R / Rfree (%)	18.7 / 22.8

The binding sites of Zinc atom in the Crystal Structure of Human Rig-I Ctd Bound to A 12 Bp Au Rich 5' Ppp Dsrna (pdb code 3lrr). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Human Rig-I Ctd Bound to A 12 Bp Au Rich 5' Ppp Dsrna, PDB code: 3lrr:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of Human Rig-I Ctd Bound to A 12 Bp Au Rich 5' Ppp Dsrna


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Human Rig-I Ctd Bound to A 12 Bp Au Rich 5' Ppp Dsrna within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1 b:33.1 occ:1.00 SG A:CYS869 2.3 43.5 1.0 SG A:CYS813 2.4 28.2 1.0 SG A:CYS864 2.4 34.5 1.0 SG A:CYS810 2.5 31.2 1.0 CB A:CYS864 3.1 35.5 1.0 CB A:CYS869 3.2 44.1 1.0 CB A:CYS810 3.2 27.3 1.0 CB A:CYS813 3.4 27.1 1.0 N A:CYS813 3.8 28.6 1.0 CA A:CYS813 4.2 27.6 1.0 CB A:ARG866 4.4 51.3 1.0 CB A:HIS871 4.4 33.2 1.0 CZ2 A:TRP873 4.5 25.1 1.0 CA A:CYS869 4.6 44.0 1.0 CA A:CYS864 4.6 35.6 1.0 CA A:CYS810 4.7 27.5 1.0 CB A:LYS812 4.7 30.0 1.0 N A:HIS871 4.8 36.3 1.0 C A:CYS813 4.8 28.2 1.0 NE1 A:TRP873 4.8 26.1 1.0 CD A:ARG866 4.8 58.8 1.0 C A:LYS812 4.9 29.5 1.0 N A:SER870 4.9 40.4 1.0 N A:LYS814 5.0 27.9 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of Human Rig-I Ctd Bound to A 12 Bp Au Rich 5' Ppp Dsrna


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Human Rig-I Ctd Bound to A 12 Bp Au Rich 5' Ppp Dsrna within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn2 b:37.2 occ:1.00 SG B:CYS869 2.3 37.9 1.0 SG B:CYS864 2.4 33.9 1.0 SG B:CYS813 2.5 38.6 1.0 SG B:CYS810 2.6 27.3 1.0 CB B:CYS869 3.1 37.4 1.0 CB B:CYS813 3.2 32.7 1.0 CB B:CYS810 3.3 27.3 1.0 CB B:CYS864 3.3 32.5 1.0 N B:CYS813 3.6 31.6 1.0 CA B:CYS813 4.0 32.3 1.0 CB B:HIS871 4.2 33.2 1.0 CB B:ARG866 4.4 46.5 1.0 CB B:LYS812 4.4 30.4 1.0 CA B:CYS869 4.5 38.3 1.0 C B:CYS813 4.7 31.8 1.0 CZ2 B:TRP873 4.7 22.6 1.0 N B:HIS871 4.7 33.7 1.0 C B:LYS812 4.7 30.4 1.0 CA B:CYS810 4.7 29.2 1.0 CA B:CYS864 4.8 32.3 1.0 N B:SER870 4.8 35.8 1.0 C B:CYS869 4.9 36.8 1.0 N B:LYS814 4.9 31.4 1.0 NE1 B:TRP873 4.9 25.0 1.0 CB B:ALA815 5.0 30.2 1.0 CA B:LYS812 5.0 30.6 1.0

C.Lu, H.Xu, C.T.Ranjith-Kumar, M.T.Brooks, T.Y.Hou, F.Hu, A.B.Herr, R.K.Strong, C.C.Kao, P.Li. The Structural Basis of 5' Triphosphate Double-Stranded Rna Recognition By Rig-I C-Terminal Domain. Structure V. 18 1032 2010.
ISSN: ISSN 0969-2126
PubMed: 20637642
DOI: 10.1016/J.STR.2010.05.007