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Atomistry » Zinc » PDB 3hk5-3hqy » 3hkq | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Zinc » PDB 3hk5-3hqy » 3hkq » |
Zinc in PDB 3hkq: Human Carbonic Anhydrase II in Complex with 1-S-D- GalactopyranosylsulfonamideEnzymatic activity of Human Carbonic Anhydrase II in Complex with 1-S-D- Galactopyranosylsulfonamide
All present enzymatic activity of Human Carbonic Anhydrase II in Complex with 1-S-D- Galactopyranosylsulfonamide:
4.2.1.1; Protein crystallography data
The structure of Human Carbonic Anhydrase II in Complex with 1-S-D- Galactopyranosylsulfonamide, PDB code: 3hkq
was solved by
B.Paul,
S.-A.Poulsen,
A.Hofmann,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Zinc Binding Sites:
The binding sites of Zinc atom in the Human Carbonic Anhydrase II in Complex with 1-S-D- Galactopyranosylsulfonamide
(pdb code 3hkq). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Human Carbonic Anhydrase II in Complex with 1-S-D- Galactopyranosylsulfonamide, PDB code: 3hkq: Zinc binding site 1 out of 1 in 3hkqGo back to![]() ![]()
Zinc binding site 1 out
of 1 in the Human Carbonic Anhydrase II in Complex with 1-S-D- Galactopyranosylsulfonamide
![]() Mono view ![]() Stereo pair view
Reference:
M.Lopez,
B.Paul,
A.Hofmann,
J.Morizzi,
Q.K.Wu,
S.A.Charman,
A.Innocenti,
D.Vullo,
C.T.Supuran,
S.A.Poulsen.
S-Glycosyl Primary Sulfonamides--A New Structural Class For Selective Inhibition of Cancer-Associated Carbonic Anhydrases. J.Med.Chem. V. 52 6421 2009.
Page generated: Thu Oct 24 14:29:28 2024
ISSN: ISSN 0022-2623 PubMed: 19827837 DOI: 10.1021/JM900914E |
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