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Atomistry » Zinc » PDB 3ful-3g8r » 3fw3 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Zinc » PDB 3ful-3g8r » 3fw3 » |
Zinc in PDB 3fw3: Crystal Structure of Soluble Domain of CA4 in Complex with DorzolamideEnzymatic activity of Crystal Structure of Soluble Domain of CA4 in Complex with Dorzolamide
All present enzymatic activity of Crystal Structure of Soluble Domain of CA4 in Complex with Dorzolamide:
4.2.1.1; Protein crystallography data
The structure of Crystal Structure of Soluble Domain of CA4 in Complex with Dorzolamide, PDB code: 3fw3
was solved by
S.E.Greasley,
R.A.A.Ferre,
R.Paz,
J.Wickersham,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of Soluble Domain of CA4 in Complex with Dorzolamide
(pdb code 3fw3). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Soluble Domain of CA4 in Complex with Dorzolamide, PDB code: 3fw3: Jump to Zinc binding site number: 1; 2; Zinc binding site 1 out of 2 in 3fw3Go back to![]() ![]()
Zinc binding site 1 out
of 2 in the Crystal Structure of Soluble Domain of CA4 in Complex with Dorzolamide
![]() Mono view ![]() Stereo pair view
Zinc binding site 2 out of 2 in 3fw3Go back to![]() ![]()
Zinc binding site 2 out
of 2 in the Crystal Structure of Soluble Domain of CA4 in Complex with Dorzolamide
![]() Mono view ![]() Stereo pair view
Reference:
W.Vernier,
W.Chong,
D.Rewolinski,
S.Greasley,
T.Pauly,
M.Shaw,
D.Dinh,
R.A.Ferre,
S.Nukui,
M.Ornelas,
E.Reyner.
Thioether Benzenesulfonamide Inhibitors of Carbonic Anhydrases II and IV: Structure-Based Drug Design, Synthesis, and Biological Evaluation. Bioorg.Med.Chem. V. 18 3307 2010.
Page generated: Thu Oct 24 13:27:23 2024
ISSN: ISSN 0968-0896 PubMed: 20363633 DOI: 10.1016/J.BMC.2010.03.014 |
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