|
Atomistry » Zinc » PDB 3ebe-3ekl » 3edz | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Zinc » PDB 3ebe-3ekl » 3edz » |
Zinc in PDB 3edz: Crystal Structure of Catalytic Domain of Tace with Hydroxamate InhibitorEnzymatic activity of Crystal Structure of Catalytic Domain of Tace with Hydroxamate Inhibitor
All present enzymatic activity of Crystal Structure of Catalytic Domain of Tace with Hydroxamate Inhibitor:
3.4.24.86; Protein crystallography data
The structure of Crystal Structure of Catalytic Domain of Tace with Hydroxamate Inhibitor, PDB code: 3edz
was solved by
R.D.Mazzola,
Z.Zhu,
L.Sinning,
B.Mckittrick,
B.Lavey,
J.Spitler,
J.Kozlowski,
S.Neng-Yang,
G.Zhou,
Z.Guo,
P.Orth,
V.Madison,
J.Sun,
D.Lundell,
X.Niu,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of Catalytic Domain of Tace with Hydroxamate Inhibitor
(pdb code 3edz). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Catalytic Domain of Tace with Hydroxamate Inhibitor, PDB code: 3edz: Jump to Zinc binding site number: 1; 2; Zinc binding site 1 out of 2 in 3edzGo back to![]() ![]()
Zinc binding site 1 out
of 2 in the Crystal Structure of Catalytic Domain of Tace with Hydroxamate Inhibitor
![]() Mono view ![]() Stereo pair view
Zinc binding site 2 out of 2 in 3edzGo back to![]() ![]()
Zinc binding site 2 out
of 2 in the Crystal Structure of Catalytic Domain of Tace with Hydroxamate Inhibitor
![]() Mono view ![]() Stereo pair view
Reference:
R.D.Mazzola,
Z.Zhu,
L.Sinning,
B.Mckittrick,
B.Lavey,
J.Spitler,
J.Kozlowski,
S.Neng-Yang,
G.Zhou,
Z.Guo,
P.Orth,
V.Madison,
J.Sun,
D.Lundell,
X.Niu.
Discovery of Novel Hydroxamates As Highly Potent Tumor Necrosis Factor-Alpha Converting Enzyme Inhibitors. Part II: Optimization of the S3' Pocket. Bioorg.Med.Chem.Lett. V. 18 5809 2008.
Page generated: Thu Oct 24 12:46:12 2024
ISSN: ISSN 0960-894X PubMed: 18835710 DOI: 10.1016/J.BMCL.2008.09.045 |
Last articlesFe in 2YXOFe in 2YRS Fe in 2YXC Fe in 2YNM Fe in 2YVJ Fe in 2YP1 Fe in 2YU2 Fe in 2YU1 Fe in 2YQB Fe in 2YOO |
© Copyright 2008-2020 by atomistry.com | ||
Home | Site Map | Copyright | Contact us | Privacy |