Atomistry » Zinc » PDB 3czt-3d7s » 3d4y
Atomistry »
  Zinc »
    PDB 3czt-3d7s »
      3d4y »

Zinc in PDB 3d4y: Golgi Mannosidase II Complex with Mannoimidazole

Enzymatic activity of Golgi Mannosidase II Complex with Mannoimidazole

All present enzymatic activity of Golgi Mannosidase II Complex with Mannoimidazole:
3.2.1.114;

Protein crystallography data

The structure of Golgi Mannosidase II Complex with Mannoimidazole, PDB code: 3d4y was solved by D.A.Kuntz, C.A.Tarling, S.G.Withers, D.R.Rose, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 30.00 / 1.52
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 68.634, 108.798, 137.035, 90.00, 90.00, 90.00
R / Rfree (%) 18.6 / 20.8

Zinc Binding Sites:

The binding sites of Zinc atom in the Golgi Mannosidase II Complex with Mannoimidazole (pdb code 3d4y). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Golgi Mannosidase II Complex with Mannoimidazole, PDB code: 3d4y:

Zinc binding site 1 out of 1 in 3d4y

Go back to Zinc Binding Sites List in 3d4y
Zinc binding site 1 out of 1 in the Golgi Mannosidase II Complex with Mannoimidazole


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Golgi Mannosidase II Complex with Mannoimidazole within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn1047

b:20.7
occ:1.00
O2 A:MVL1049 2.1 29.2 1.0
NE2 A:HIS90 2.1 19.1 1.0
NE2 A:HIS471 2.1 17.2 1.0
OD2 A:ASP204 2.2 21.6 1.0
OD1 A:ASP92 2.2 20.6 1.0
O3 A:MVL1049 2.2 18.2 1.0
CD2 A:HIS471 3.0 17.6 1.0
CE1 A:HIS90 3.1 17.4 1.0
CG A:ASP92 3.1 19.9 1.0
CD2 A:HIS90 3.1 21.2 1.0
C2 A:MVL1049 3.1 23.6 1.0
C3 A:MVL1049 3.1 18.9 1.0
CE1 A:HIS471 3.1 19.1 1.0
CG A:ASP204 3.2 22.3 1.0
OD2 A:ASP92 3.3 23.1 1.0
CB A:ASP204 3.6 19.1 1.0
C4 A:MVL1049 4.0 18.8 1.0
OD2 A:ASP472 4.1 19.3 1.0
ND1 A:HIS90 4.2 19.3 1.0
CG A:HIS90 4.2 18.6 1.0
CG A:HIS471 4.2 17.1 1.0
ND1 A:HIS471 4.2 17.1 1.0
OD1 A:ASP204 4.3 24.0 1.0
C1 A:MVL1049 4.4 26.6 1.0
CE1 A:HIS470 4.4 18.6 1.0
CB A:ASP92 4.4 18.0 1.0
O A:HOH1846 4.6 21.0 1.0
OH A:TYR269 4.8 25.2 1.0
O4 A:MVL1049 4.8 19.3 1.0
CA A:ASP92 5.0 17.3 1.0

Reference:

D.A.Kuntz, C.A.Tarling, S.G.Withers, D.R.Rose. Structural Analysis of Golgi Alpha-Mannosidase II Inhibitors Identified From A Focused Glycosidase Inhibitor Screen. Biochemistry V. 47 10058 2008.
ISSN: ISSN 0006-2960
PubMed: 18759458
DOI: 10.1021/BI8010785
Page generated: Thu Oct 24 12:03:05 2024

Last articles

Zn in 9MJ5
Zn in 9HNW
Zn in 9G0L
Zn in 9FNE
Zn in 9DZN
Zn in 9E0I
Zn in 9D32
Zn in 9DAK
Zn in 8ZXC
Zn in 8ZUF
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy