Atomistry » Zinc » PDB 2vr6-2w15 » 2vva
Atomistry »
  Zinc »
    PDB 2vr6-2w15 »
      2vva »

Zinc in PDB 2vva: Human Carbonic Anhydrase in Complex with CO2

Enzymatic activity of Human Carbonic Anhydrase in Complex with CO2

All present enzymatic activity of Human Carbonic Anhydrase in Complex with CO2:
4.2.1.1;

Protein crystallography data

The structure of Human Carbonic Anhydrase in Complex with CO2, PDB code: 2vva was solved by B.Sjoeblom, M.Polentarutti, K.Djinovic-Carugo, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 70.19 / 1.56
Space group P 1 21 1
Cell size a, b, c (Å), α, β, γ (°) 42.589, 41.577, 72.636, 90.00, 104.84, 90.00
R / Rfree (%) 15.3 / 20

Zinc Binding Sites:

The binding sites of Zinc atom in the Human Carbonic Anhydrase in Complex with CO2 (pdb code 2vva). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Human Carbonic Anhydrase in Complex with CO2, PDB code: 2vva:

Zinc binding site 1 out of 1 in 2vva

Go back to Zinc Binding Sites List in 2vva
Zinc binding site 1 out of 1 in the Human Carbonic Anhydrase in Complex with CO2


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Human Carbonic Anhydrase in Complex with CO2 within 5.0Å range:
probe atom residue distance (Å) B Occ
X:Zn1267

b:7.3
occ:1.00
O X:HOH2350 2.0 9.9 1.0
ND1 X:HIS119 2.0 6.0 1.0
NE2 X:HIS96 2.0 6.4 1.0
NE2 X:HIS94 2.0 5.5 1.0
CE1 X:HIS119 2.9 5.4 1.0
CD2 X:HIS94 2.9 6.1 1.0
CD2 X:HIS96 3.0 5.6 1.0
CE1 X:HIS96 3.0 8.0 1.0
CE1 X:HIS94 3.1 7.8 1.0
CG X:HIS119 3.1 5.1 1.0
O1 X:CO21264 3.2 12.4 1.0
CB X:HIS119 3.6 6.2 1.0
O X:HOH2258 3.6 14.9 1.0
C X:CO21264 3.7 17.4 1.0
OG1 X:THR199 3.8 6.6 1.0
OE1 X:GLU106 4.0 7.5 1.0
NE2 X:HIS119 4.1 6.2 1.0
CG X:HIS94 4.1 5.7 1.0
CG X:HIS96 4.1 5.6 1.0
ND1 X:HIS96 4.1 7.6 1.0
ND1 X:HIS94 4.2 6.4 1.0
CD2 X:HIS119 4.2 5.5 1.0
O X:HOH2001 4.3 16.5 1.0
O2 X:CO21264 4.5 16.5 1.0
O X:HOH2260 4.8 18.9 1.0
CD X:GLU106 4.8 7.8 1.0
O X:HOH2342 5.0 20.2 1.0

Reference:

B.Sjoblom, M.Polentarutti, K.Djinovic-Carugo. Structural Study of X-Ray Induced Activation of Carbonic Anhydrase. Proc.Natl.Acad.Sci.Usa V. 106 10609 2009.
ISSN: ISSN 0027-8424
PubMed: 19520834
DOI: 10.1073/PNAS.0904184106
Page generated: Thu Oct 17 04:37:20 2024

Last articles

Zn in 9MJ5
Zn in 9HNW
Zn in 9G0L
Zn in 9FNE
Zn in 9DZN
Zn in 9E0I
Zn in 9D32
Zn in 9DAK
Zn in 8ZXC
Zn in 8ZUF
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy