Zinc in PDB 2v1c: Crystal Structure and Mutational Study of Recor Provide Insight Into Its Role in Dna Repair

The structure of Crystal Structure and Mutational Study of Recor Provide Insight Into Its Role in Dna Repair, PDB code: 2v1c was solved by J.Timmins, I.Leiros, S.Mcsweeney, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	71.25 / 3.80
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	144.000, 83.200, 66.600, 90.00, 106.90, 90.00
R / Rfree (%)	45.9 / 44.3

The binding sites of Zinc atom in the Crystal Structure and Mutational Study of Recor Provide Insight Into Its Role in Dna Repair (pdb code 2v1c). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 3 binding sites of Zinc where determined in the Crystal Structure and Mutational Study of Recor Provide Insight Into Its Role in Dna Repair, PDB code: 2v1c:
Jump to Zinc binding site number: 1; 2; 3;

Zinc binding site 1 out of 3 in the Crystal Structure and Mutational Study of Recor Provide Insight Into Its Role in Dna Repair


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure and Mutational Study of Recor Provide Insight Into Its Role in Dna Repair within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn230 b:96.0 occ:1.00 SG A:CYS60 1.9 96.0 1.0 SG A:CYS69 2.0 96.0 1.0 SG A:CYS72 2.2 96.0 1.0 SG A:CYS57 2.5 96.0 1.0 CB A:CYS69 2.9 96.0 1.0 CB A:CYS72 3.3 96.0 1.0 CB A:CYS57 3.4 96.0 1.0 CB A:CYS60 3.5 96.0 1.0 N A:CYS69 3.6 96.0 1.0 N A:CYS60 3.8 96.0 1.0 CA A:CYS69 3.8 96.0 1.0 O A:CYS60 3.9 96.0 1.0 CA A:CYS60 4.1 96.0 1.0 N A:CYS72 4.1 96.0 1.0 C A:CYS60 4.2 96.0 1.0 CA A:CYS72 4.3 96.0 1.0 CB A:ILE59 4.4 96.0 1.0 C A:CYS69 4.5 96.0 1.0 O A:CYS69 4.6 96.0 1.0 CB A:ASN62 4.6 96.0 1.0 C A:LYS68 4.8 96.0 1.0 N A:ASN62 4.9 96.0 1.0 C A:ILE59 4.9 96.0 1.0 CA A:CYS57 4.9 96.0 1.0

Zinc binding site 2 out of 3 in the Crystal Structure and Mutational Study of Recor Provide Insight Into Its Role in Dna Repair


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure and Mutational Study of Recor Provide Insight Into Its Role in Dna Repair within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn230 b:96.0 occ:1.00 SG B:CYS60 1.9 96.0 1.0 SG B:CYS69 2.0 96.0 1.0 SG B:CYS72 2.2 96.0 1.0 SG B:CYS57 2.5 96.0 1.0 CB B:CYS69 2.9 96.0 1.0 CB B:CYS72 3.3 96.0 1.0 CB B:CYS57 3.4 96.0 1.0 CB B:CYS60 3.5 96.0 1.0 N B:CYS69 3.6 96.0 1.0 N B:CYS60 3.8 96.0 1.0 CA B:CYS69 3.8 96.0 1.0 O B:CYS60 3.9 96.0 1.0 CA B:CYS60 4.1 96.0 1.0 N B:CYS72 4.1 96.0 1.0 C B:CYS60 4.2 96.0 1.0 CA B:CYS72 4.3 96.0 1.0 CB B:ILE59 4.4 96.0 1.0 C B:CYS69 4.5 96.0 1.0 O B:CYS69 4.6 96.0 1.0 CB B:ASN62 4.6 96.0 1.0 C B:LYS68 4.8 96.0 1.0 N B:ASN62 4.9 96.0 1.0 C B:ILE59 4.9 96.0 1.0 CA B:CYS57 4.9 96.0 1.0

Zinc binding site 3 out of 3 in the Crystal Structure and Mutational Study of Recor Provide Insight Into Its Role in Dna Repair


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Crystal Structure and Mutational Study of Recor Provide Insight Into Its Role in Dna Repair within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn266 b:96.0 occ:1.00 SG C:CYS156 2.3 96.0 1.0 SG C:CYS153 2.3 96.0 1.0 SG C:CYS176 2.4 96.0 1.0 SG C:CYS173 2.4 96.0 1.0 CB C:CYS153 3.2 96.0 1.0 CB C:CYS156 3.2 96.0 1.0 CB C:CYS176 3.3 96.0 1.0 CB C:CYS173 3.6 96.0 1.0 N C:CYS156 3.6 96.0 1.0 CA C:CYS156 4.0 96.0 1.0 N C:CYS173 4.0 96.0 1.0 N C:CYS176 4.3 96.0 1.0 CA C:CYS173 4.3 96.0 1.0 CA C:CYS176 4.4 96.0 1.0 CB C:ARG155 4.6 96.0 1.0 CA C:CYS153 4.7 96.0 1.0 CB C:ALA158 4.7 96.0 1.0 N C:GLY157 4.7 96.0 1.0 C C:CYS156 4.7 96.0 1.0 C C:ARG155 4.7 96.0 1.0 N C:ALA158 4.9 96.0 1.0 C C:CYS173 4.9 96.0 1.0 O C:CYS173 4.9 96.0 1.0 N C:ARG155 5.0 96.0 1.0 CA C:ARG155 5.0 96.0 1.0

J.Timmins, I.Leiros, S.Mcsweeney. Crystal Structure and Mutational Study of Recor Provide Insight Into Its Mode of Dna Binding. Embo J. V. 26 3260 2007.
ISSN: ISSN 0261-4189
PubMed: 17581636
DOI: 10.1038/SJ.EMBOJ.7601760