Zinc in PDB 2p1h: Rapid Folding and Unfolding of Apaf-1 Card

The structure of Rapid Folding and Unfolding of Apaf-1 Card, PDB code: 2p1h was solved by S.L.Milam, N.I.Nicely, B.Feeney, C.Mattos, A.C.Clark, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	35.90 / 1.59
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	33.468, 47.515, 54.746, 90.00, 90.00, 90.00
R / Rfree (%)	23.9 / 29.7

The binding sites of Zinc atom in the Rapid Folding and Unfolding of Apaf-1 Card (pdb code 2p1h). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 6 binding sites of Zinc where determined in the Rapid Folding and Unfolding of Apaf-1 Card, PDB code: 2p1h:
Jump to Zinc binding site number: 1; 2; 3; 4; 5; 6;

Zinc binding site 1 out of 6 in the Rapid Folding and Unfolding of Apaf-1 Card


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Rapid Folding and Unfolding of Apaf-1 Card within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn101 b:47.3 occ:1.00 OE2 A:GLU42 2.2 39.8 1.0 OD1 A:ASP29 2.5 52.4 1.0 OE1 A:GLU42 2.6 40.2 1.0 CD A:GLU42 2.7 38.7 1.0 CG A:ASP29 3.3 50.0 1.0 OD2 A:ASP29 3.5 53.8 1.0 CG A:GLU42 4.2 39.7 1.0 CD1 A:ILE32 4.2 40.0 1.0 CB A:ASP29 4.5 45.3 1.0 CA A:ASP29 4.6 40.0 1.0 O A:HOH138 5.0 43.7 1.0

Zinc binding site 2 out of 6 in the Rapid Folding and Unfolding of Apaf-1 Card


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Rapid Folding and Unfolding of Apaf-1 Card within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn102 b:68.5 occ:0.50 OD2 A:ASP34 2.3 50.9 1.0 NE2 A:HIS30 2.4 43.2 1.0 O A:HOH152 2.6 59.0 1.0 CD2 A:HIS30 2.9 41.7 1.0 O A:HOH131 3.2 47.8 1.0 CG A:ASP34 3.6 49.2 1.0 CE1 A:HIS30 3.6 43.4 1.0 CD2 A:HIS79 3.7 54.1 1.0 OD1 A:ASP34 4.2 49.7 1.0 CB A:ASN75 4.2 31.9 1.0 CG A:HIS30 4.2 40.5 1.0 ZN A:ZN105 4.3 94.1 1.0 NE2 A:HIS79 4.3 54.7 1.0 ND1 A:HIS30 4.5 42.9 1.0 O A:ASN75 4.6 34.3 1.0 CB A:ASP34 4.6 43.7 1.0 C A:ASN75 4.7 32.8 1.0 CG A:HIS79 4.8 52.8 1.0 N A:ALA76 5.0 33.0 1.0

Zinc binding site 3 out of 6 in the Rapid Folding and Unfolding of Apaf-1 Card


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Rapid Folding and Unfolding of Apaf-1 Card within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn103 b:59.3 occ:1.00 NE2 A:HIS14 2.3 34.3 1.0 O A:HOH115 2.4 54.3 1.0 CD2 A:HIS14 3.2 34.9 1.0 O A:HOH143 3.2 25.3 1.0 CE1 A:HIS14 3.2 35.2 1.0 ZN A:ZN104 3.2 41.5 1.0 O A:LEU88 4.2 38.9 1.0 SG A:CYS10 4.2 43.8 1.0 ND1 A:HIS14 4.3 35.5 1.0 CG A:HIS14 4.3 35.5 1.0 CB A:GLN13 4.7 39.4 1.0 OD2 A:ASP91 4.7 45.4 1.0 O A:CYS10 4.8 37.6 1.0 OD1 A:ASP91 4.9 43.7 1.0

Zinc binding site 4 out of 6 in the Rapid Folding and Unfolding of Apaf-1 Card


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Rapid Folding and Unfolding of Apaf-1 Card within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn104 b:41.5 occ:1.00 OD1 A:ASP91 2.2 43.7 1.0 SG A:CYS10 2.3 43.8 1.0 OD2 A:ASP91 2.7 45.4 1.0 CG A:ASP91 2.8 42.3 1.0 O A:HOH143 3.1 25.3 1.0 CB A:CYS10 3.2 41.6 1.0 ZN A:ZN103 3.2 59.3 1.0 O A:LEU88 3.6 38.9 1.0 O A:HOH115 3.8 54.3 1.0 CA A:CYS10 4.0 39.4 1.0 N A:GLY92 4.2 42.8 1.0 CB A:ASP91 4.3 40.4 1.0 C A:ASP91 4.6 41.7 1.0 O A:HOH140 4.6 32.6 1.0 NE2 A:HIS14 4.6 34.3 1.0 CA A:GLY92 4.7 43.0 1.0 CD2 A:HIS14 4.8 34.9 1.0 C A:LEU88 4.8 37.8 1.0 CA A:ASP91 4.8 41.2 1.0 C A:CYS10 4.9 37.7 1.0 N A:ASP91 4.9 38.5 1.0 O A:CYS10 5.0 37.6 1.0 O A:HOH132 5.0 38.4 1.0

Zinc binding site 5 out of 6 in the Rapid Folding and Unfolding of Apaf-1 Card


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 5 of Rapid Folding and Unfolding of Apaf-1 Card within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn105 b:94.1 occ:1.00 NE2 A:HIS79 2.3 54.7 1.0 O A:HOH152 2.9 59.0 1.0 CE1 A:HIS79 3.1 55.6 1.0 CD2 A:HIS79 3.3 54.1 1.0 ND1 A:HIS79 4.3 54.2 1.0 ZN A:ZN102 4.3 68.5 0.5 CG A:HIS79 4.4 52.8 1.0 CG A:ASN75 4.8 36.7 1.0 CB A:ASN75 4.8 31.9 1.0 OD1 A:ASN75 5.0 37.0 1.0

Zinc binding site 6 out of 6 in the Rapid Folding and Unfolding of Apaf-1 Card


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 6 of Rapid Folding and Unfolding of Apaf-1 Card within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn106 b:46.3 occ:1.00 OD2 A:ASP66 2.0 28.4 1.0 OD2 A:ASP68 2.3 44.9 1.0 O A:HOH154 2.4 27.9 1.0 CG A:ASP66 2.8 39.3 1.0 OD1 A:ASP68 2.9 43.6 1.0 CG A:ASP68 2.9 42.6 1.0 OD1 A:ASP66 3.0 37.3 1.0 O A:HOH110 3.9 39.2 1.0 OG A:SER69 4.1 38.4 1.0 CB A:ASP66 4.2 34.7 1.0 CB A:ASP68 4.4 39.1 1.0 CD1 A:PHE36 4.7 33.1 1.0 N A:SER69 4.8 33.0 1.0 CE1 A:PHE36 4.9 28.0 1.0

S.L.Milam, N.I.Nicely, B.Feeney, C.Mattos, A.C.Clark. Rapid Folding and Unfolding of Apaf-1 Card. J.Mol.Biol. V. 369 290 2007.
ISSN: ISSN 0022-2836
PubMed: 17408690
DOI: 10.1016/J.JMB.2007.02.105