Zinc in PDB 2od9: Structural Basis For Nicotinamide Inhibition and Base Exchange in SIR2 Enzymes

The structure of Structural Basis For Nicotinamide Inhibition and Base Exchange in SIR2 Enzymes, PDB code: 2od9 was solved by R.Marmorstein, B.D.Sanders, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	28.34 / 2.05
Space group	P 32 2 1
Cell size a, b, c (Å), α, β, γ (°)	105.940, 105.940, 67.100, 90.00, 90.00, 120.00
R / Rfree (%)	21.8 / 24.5

The binding sites of Zinc atom in the Structural Basis For Nicotinamide Inhibition and Base Exchange in SIR2 Enzymes (pdb code 2od9). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Structural Basis For Nicotinamide Inhibition and Base Exchange in SIR2 Enzymes, PDB code: 2od9:

Zinc binding site 1 out of 1 in the Structural Basis For Nicotinamide Inhibition and Base Exchange in SIR2 Enzymes


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structural Basis For Nicotinamide Inhibition and Base Exchange in SIR2 Enzymes within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn701 b:31.3 occ:1.00 SG A:CYS170 2.3 25.5 1.0 SG A:CYS146 2.4 26.2 1.0 SG A:CYS143 2.4 22.9 1.0 SG A:CYS173 2.5 23.6 1.0 CB A:CYS143 3.1 27.0 1.0 CB A:CYS170 3.1 22.6 1.0 CB A:CYS146 3.2 30.0 1.0 CB A:CYS173 3.4 21.1 1.0 N A:CYS146 3.5 26.4 1.0 N A:CYS173 3.7 24.3 1.0 CA A:CYS146 3.9 25.5 1.0 CA A:CYS173 4.1 22.9 1.0 CB A:VAL172 4.4 24.1 1.0 C A:CYS146 4.6 31.4 1.0 C A:GLY145 4.6 37.1 1.0 CA A:CYS143 4.6 23.9 1.0 CA A:CYS170 4.6 20.5 1.0 N A:GLY147 4.6 27.6 1.0 CB A:LYS148 4.7 24.2 1.0 C A:CYS173 4.7 26.4 1.0 C A:VAL172 4.7 25.8 1.0 CG1 A:VAL172 4.7 25.7 1.0 N A:GLY174 4.7 19.8 1.0 N A:LYS148 4.8 25.2 1.0 CA A:GLY145 4.9 33.7 1.0 N A:GLY145 4.9 30.2 1.0 N A:GLU175 4.9 20.6 1.0 CA A:VAL172 5.0 25.9 1.0

B.D.Sanders, K.Zhao, J.T.Slama, R.Marmorstein. Structural Basis For Nicotinamide Inhibition and Base Exchange in SIR2 Enzymes. Mol.Cell V. 25 463 2007.
ISSN: ISSN 1097-2765
PubMed: 17289592
DOI: 10.1016/J.MOLCEL.2006.12.022