Zinc in PDB 2od1: Solution Structure of the Mynd Domain From Human AML1-Eto

The binding sites of Zinc atom in the Solution Structure of the Mynd Domain From Human AML1-Eto (pdb code 2od1). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Solution Structure of the Mynd Domain From Human AML1-Eto, PDB code: 2od1:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Solution Structure of the Mynd Domain From Human AML1-Eto


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Solution Structure of the Mynd Domain From Human AML1-Eto within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn901 b:0.0 occ:1.00 SG A:CYS663 2.3 0.0 1.0 SG A:CYS683 2.3 0.0 1.0 SG A:CYS666 2.3 0.0 1.0 SG A:CYS687 2.3 0.0 1.0 HB2 A:CYS666 2.9 0.0 1.0 H A:CYS683 2.9 0.0 1.0 H A:CYS666 3.0 0.0 1.0 CB A:CYS666 3.2 0.0 1.0 HD21 A:ASN665 3.3 0.0 1.0 CB A:CYS663 3.4 0.0 1.0 HB3 A:CYS683 3.4 0.0 1.0 HB2 A:CYS663 3.4 0.0 1.0 CB A:CYS687 3.4 0.0 1.0 HB3 A:CYS687 3.5 0.0 1.0 CB A:CYS683 3.5 0.0 1.0 HB3 A:CYS663 3.5 0.0 1.0 HB2 A:CYS687 3.6 0.0 1.0 N A:CYS683 3.8 0.0 1.0 N A:CYS666 3.8 0.0 1.0 HB3 A:ASN665 3.8 0.0 1.0 HB3 A:CYS666 4.0 0.0 1.0 CA A:CYS666 4.1 0.0 1.0 CA A:CYS683 4.2 0.0 1.0 H A:GLY684 4.2 0.0 1.0 HZ A:PHE686 4.2 0.0 1.0 ND2 A:ASN665 4.2 0.0 1.0 HB3 A:TYR682 4.3 0.0 1.0 HB2 A:CYS683 4.3 0.0 1.0 HD1 A:TYR682 4.4 0.0 1.0 HA A:TYR682 4.4 0.0 1.0 H A:ASN665 4.4 0.0 1.0 HE2 A:PHE686 4.5 0.0 1.0 HA A:CYS666 4.5 0.0 1.0 CZ A:PHE686 4.6 0.0 1.0 N A:GLY684 4.7 0.0 1.0 CB A:ASN665 4.8 0.0 1.0 CE2 A:PHE686 4.8 0.0 1.0 CA A:CYS663 4.8 0.0 1.0 HD22 A:ASN665 4.8 0.0 1.0 C A:CYS683 4.8 0.0 1.0 O A:LYS669 4.8 0.0 1.0 C A:TYR682 4.8 0.0 1.0 CA A:CYS687 4.8 0.0 1.0 HA A:CYS687 5.0 0.0 1.0 C A:ASN665 5.0 0.0 1.0

Zinc binding site 2 out of 2 in the Solution Structure of the Mynd Domain From Human AML1-Eto


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Solution Structure of the Mynd Domain From Human AML1-Eto within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn902 b:0.0 occ:1.00 NE2 A:HIS695 2.0 0.0 1.0 SG A:CYS674 2.3 0.0 1.0 SG A:CYS699 2.3 0.0 1.0 SG A:CYS677 2.3 0.0 1.0 CD2 A:HIS695 2.9 0.0 1.0 CE1 A:HIS695 3.0 0.0 1.0 HB3 A:CYS677 3.0 0.0 1.0 HD2 A:HIS695 3.1 0.0 1.0 CB A:CYS677 3.2 0.0 1.0 HE1 A:HIS695 3.3 0.0 1.0 HB3 A:ALA680 3.3 0.0 1.0 HB2 A:CYS699 3.3 0.0 1.0 CB A:CYS674 3.4 0.0 1.0 HB3 A:CYS674 3.4 0.0 1.0 H A:CYS677 3.4 0.0 1.0 HB2 A:CYS674 3.5 0.0 1.0 CB A:CYS699 3.5 0.0 1.0 N A:CYS677 3.8 0.0 1.0 CG A:HIS695 4.0 0.0 1.0 ND1 A:HIS695 4.0 0.0 1.0 H A:ALA680 4.0 0.0 1.0 HB2 A:CYS677 4.1 0.0 1.0 CA A:CYS677 4.1 0.0 1.0 HB3 A:CYS699 4.2 0.0 1.0 CB A:ALA680 4.3 0.0 1.0 HA A:CYS699 4.3 0.0 1.0 HA3 A:GLY676 4.4 0.0 1.0 H A:GLY676 4.5 0.0 1.0 C A:GLY676 4.5 0.0 1.0 HB2 A:ALA680 4.5 0.0 1.0 CA A:CYS699 4.6 0.0 1.0 H A:THR679 4.6 0.0 1.0 HB A:THR679 4.8 0.0 1.0 CA A:CYS674 4.8 0.0 1.0 HB1 A:ALA680 4.8 0.0 1.0 H A:ASN678 4.8 0.0 1.0 HD1 A:HIS695 4.9 0.0 1.0 CA A:GLY676 4.9 0.0 1.0 N A:ALA680 4.9 0.0 1.0 HD13 A:ILE698 4.9 0.0 1.0 HA A:CYS677 4.9 0.0 1.0 H A:GLY700 5.0 0.0 1.0 C A:CYS677 5.0 0.0 1.0

Y.Liu, W.Chen, J.Gaudet, M.D.Cheney, L.Roudaia, T.Cierpicki, R.C.Klet, K.Hartman, T.M.Laue, N.A.Speck, J.H.Bushweller. Structural Basis For Recognition of Smrt/N-Cor By the Mynd Domain and Its Contribution to AML1/Eto'S Activity. Cancer Cell V. 11 483 2007.
ISSN: ISSN 1535-6108
PubMed: 17560331
DOI: 10.1016/J.CCR.2007.04.010