Zinc in PDB 2m1r: Phd Domain of ING4 N214D Mutant

The binding sites of Zinc atom in the Phd Domain of ING4 N214D Mutant (pdb code 2m1r). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Phd Domain of ING4 N214D Mutant, PDB code: 2m1r:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Phd Domain of ING4 N214D Mutant


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Phd Domain of ING4 N214D Mutant within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn301 b:0.0 occ:1.00 HB2 A:HIS223 2.0 0.0 1.0 HB2 A:CYS201 2.2 0.0 1.0 OH A:TYR206 2.2 0.0 1.0 HB2 A:CYS199 2.2 0.0 1.0 HH A:TYR206 2.4 0.0 1.0 SG A:CYS201 2.5 0.0 1.0 SG A:CYS226 2.5 0.0 1.0 HB3 A:HIS223 2.7 0.0 1.0 CB A:CYS201 2.7 0.0 1.0 CB A:HIS223 2.8 0.0 1.0 H A:CYS201 2.9 0.0 1.0 CB A:CYS199 3.0 0.0 1.0 HB3 A:CYS199 3.1 0.0 1.0 H A:HIS223 3.2 0.0 1.0 CG A:HIS223 3.4 0.0 1.0 HG A:CYS226 3.4 0.0 1.0 N A:CYS201 3.5 0.0 1.0 CZ A:TYR206 3.5 0.0 1.0 HB3 A:CYS201 3.5 0.0 1.0 ND1 A:HIS223 3.6 0.0 1.0 SG A:CYS199 3.6 0.0 1.0 CA A:CYS201 3.8 0.0 1.0 HH2 A:TRP221 3.8 0.0 1.0 H A:LEU200 3.8 0.0 1.0 N A:HIS223 3.9 0.0 1.0 CA A:HIS223 4.0 0.0 1.0 HZ2 A:TRP221 4.0 0.0 1.0 CB A:CYS226 4.1 0.0 1.0 HE2 A:TYR206 4.1 0.0 1.0 HB2 A:CYS226 4.1 0.0 1.0 CH2 A:TRP221 4.3 0.0 1.0 CE2 A:TYR206 4.3 0.0 1.0 N A:LEU200 4.3 0.0 1.0 CZ2 A:TRP221 4.3 0.0 1.0 CA A:CYS199 4.4 0.0 1.0 HE1 A:TYR206 4.4 0.0 1.0 CE1 A:TYR206 4.5 0.0 1.0 HA A:CYS201 4.5 0.0 1.0 HA A:HIS223 4.5 0.0 1.0 CD2 A:HIS223 4.5 0.0 1.0 C A:LEU200 4.5 0.0 1.0 H A:HIS202 4.5 0.0 1.0 H A:CYS226 4.6 0.0 1.0 HA A:CYS199 4.7 0.0 1.0 C A:CYS199 4.7 0.0 1.0 O A:GLN203 4.7 0.0 1.0 CE1 A:HIS223 4.7 0.0 1.0 HB2 A:LEU200 4.7 0.0 1.0 HA A:PHE222 4.7 0.0 1.0 HB3 A:CYS226 4.8 0.0 1.0 C A:CYS201 4.8 0.0 1.0 N A:CYS226 4.8 0.0 1.0 HA A:CYS226 4.8 0.0 1.0 CA A:CYS226 4.9 0.0 1.0 HG2 A:GLN203 4.9 0.0 1.0 CA A:LEU200 5.0 0.0 1.0 H A:GLN203 5.0 0.0 1.0

Zinc binding site 2 out of 2 in the Phd Domain of ING4 N214D Mutant


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Phd Domain of ING4 N214D Mutant within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn302 b:0.0 occ:1.00 HB3 A:CYS212 2.3 0.0 1.0 SG A:CYS217 2.3 0.0 1.0 HB2 A:CYS212 2.4 0.0 1.0 SG A:CYS239 2.4 0.0 1.0 HE1 A:PHE222 2.4 0.0 1.0 HB3 A:CYS239 2.7 0.0 1.0 CB A:CYS212 2.7 0.0 1.0 HG A:CYS217 2.7 0.0 1.0 HZ A:PHE222 2.9 0.0 1.0 CE1 A:PHE222 3.0 0.0 1.0 CB A:CYS239 3.1 0.0 1.0 CZ A:PHE222 3.2 0.0 1.0 H A:CYS239 3.3 0.0 1.0 SG A:CYS212 3.4 0.0 1.0 SG A:CYS242 3.4 0.0 1.0 HB2 A:CYS217 3.5 0.0 1.0 CB A:CYS217 3.6 0.0 1.0 HG A:CYS239 3.7 0.0 1.0 HB2 A:CYS239 3.7 0.0 1.0 HB A:ILE219 3.9 0.0 1.0 HB2 A:CYS242 4.0 0.0 1.0 H A:CYS212 4.0 0.0 1.0 CD1 A:PHE222 4.1 0.0 1.0 N A:CYS239 4.1 0.0 1.0 CA A:CYS212 4.1 0.0 1.0 CA A:CYS239 4.2 0.0 1.0 H A:GLU220 4.3 0.0 1.0 HB3 A:CYS217 4.3 0.0 1.0 CB A:CYS242 4.4 0.0 1.0 CE2 A:PHE222 4.4 0.0 1.0 HD1 A:PHE222 4.4 0.0 1.0 HA A:CYS217 4.5 0.0 1.0 H A:CYS242 4.5 0.0 1.0 N A:CYS212 4.5 0.0 1.0 HB3 A:ASP214 4.5 0.0 1.0 HG A:CYS242 4.7 0.0 1.0 HZ3 A:TRP237 4.7 0.0 1.0 CA A:CYS217 4.7 0.0 1.0 HA A:CYS212 4.7 0.0 1.0 H A:ILE219 4.7 0.0 1.0 HB2 A:ARG241 4.9 0.0 1.0 CB A:ILE219 4.9 0.0 1.0 HB3 A:CYS242 5.0 0.0 1.0 HE2 A:PHE222 5.0 0.0 1.0 HA A:CYS239 5.0 0.0 1.0

A.Moreno, A.Palacios, J.L.Orgaz, B.Jimenez, F.J.Blanco, I.Palmero. Functional Impact of Cancer-Associated Mutations in the Tumor Suppressor Protein ING4. Carcinogenesis V. 31 1932 2010.
PubMed: 20705953
DOI: 10.1093/CARCIN/BGQ171