Zinc in PDB 2ijd: Crystal Structure of the Poliovirus Precursor Protein 3CD

All present enzymatic activity of Crystal Structure of the Poliovirus Precursor Protein 3CD:
2.7.7.48; 3.4.22.28;

The structure of Crystal Structure of the Poliovirus Precursor Protein 3CD, PDB code: 2ijd was solved by L.L.Marcotte, D.W.Gohara, D.J.Filman, J.M.Hogle, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	19.90 / 3.40
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	208.537, 230.436, 151.035, 90.00, 90.00, 90.00
R / Rfree (%)	19.9 / 23.1

The binding sites of Zinc atom in the Crystal Structure of the Poliovirus Precursor Protein 3CD (pdb code 2ijd). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of the Poliovirus Precursor Protein 3CD, PDB code: 2ijd:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of the Poliovirus Precursor Protein 3CD


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of the Poliovirus Precursor Protein 3CD within 5.0Å range: probe atom residue distance (Å) B Occ 1:Zn645 b:25.9 occ:1.00 NE2 1:HIS453 2.1 41.2 1.0 SG 1:CYS464 2.3 42.3 1.0 CE1 1:HIS453 2.5 42.3 1.0 CE1 1:HIS455 2.5 8.1 1.0 CB 1:CYS464 2.7 38.1 1.0 ND1 1:HIS455 2.9 15.7 1.0 CD2 1:HIS453 3.2 40.4 1.0 ND1 1:HIS453 3.6 36.0 1.0 NE2 1:HIS455 3.7 33.6 1.0 NE1 1:TRP188 3.9 36.9 1.0 CG 1:HIS453 4.0 28.5 1.0 CA 1:CYS464 4.2 32.7 1.0 CG 1:HIS455 4.3 21.8 1.0 CE2 1:TRP188 4.6 32.4 1.0 CD2 1:HIS455 4.6 25.7 1.0 CZ2 1:TRP188 4.7 28.7 1.0 C 1:CYS464 4.8 32.7 1.0 CD1 1:TRP188 4.9 36.2 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of the Poliovirus Precursor Protein 3CD


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of the Poliovirus Precursor Protein 3CD within 5.0Å range: probe atom residue distance (Å) B Occ 2:Zn645 b:36.0 occ:1.00 SG 2:CYS464 2.1 21.0 1.0 NE2 2:HIS453 2.3 26.9 1.0 CE1 2:HIS453 2.4 30.9 1.0 ND1 2:HIS455 2.4 15.2 1.0 CE1 2:HIS455 2.7 16.5 1.0 CB 2:CYS464 3.2 21.4 1.0 CD2 2:HIS453 3.5 33.1 1.0 ND1 2:HIS453 3.6 28.3 1.0 CG 2:HIS455 3.8 20.0 1.0 NE1 2:TRP188 3.8 31.9 1.0 NE2 2:HIS455 4.0 31.9 1.0 CG 2:HIS453 4.1 28.0 1.0 CA 2:CYS464 4.2 19.3 1.0 CZ2 2:TRP188 4.3 29.7 1.0 CE2 2:TRP188 4.4 30.1 1.0 CB 2:HIS455 4.5 23.6 1.0 CD2 2:HIS455 4.5 20.9 1.0 C 2:CYS464 4.9 19.6 1.0 CD1 2:TRP188 4.9 33.2 1.0

L.L.Marcotte, A.B.Wass, D.W.Gohara, H.B.Pathak, J.J.Arnold, D.J.Filman, C.E.Cameron, J.M.Hogle. Crystal Structure of Poliovirus 3CD: Virally-Encoded Protease and Precursor to the Rna-Dependent Rna Polymerase. J.Virol. V. 81 3583 2007.
ISSN: ISSN 0022-538X
PubMed: 17251299
DOI: 10.1128/JVI.02306-06