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Atomistry » Zinc » PDB 2gzi-2han » 2h15 » |
Zinc in PDB 2h15: Carbonic Anhydrase Inhibitors: Clashing with ALA65 As A Means of Designing Isozyme-Selective Inhibitors That Show Low Affinity For the Ubiquitous Isozyme IIEnzymatic activity of Carbonic Anhydrase Inhibitors: Clashing with ALA65 As A Means of Designing Isozyme-Selective Inhibitors That Show Low Affinity For the Ubiquitous Isozyme II
All present enzymatic activity of Carbonic Anhydrase Inhibitors: Clashing with ALA65 As A Means of Designing Isozyme-Selective Inhibitors That Show Low Affinity For the Ubiquitous Isozyme II:
4.2.1.1; Protein crystallography data
The structure of Carbonic Anhydrase Inhibitors: Clashing with ALA65 As A Means of Designing Isozyme-Selective Inhibitors That Show Low Affinity For the Ubiquitous Isozyme II, PDB code: 2h15
was solved by
J.Y.Winum,
C.Temperini,
S.Ciattini,
A.Scozzafava,
C.T.Supuran,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 2h15:
The structure of Carbonic Anhydrase Inhibitors: Clashing with ALA65 As A Means of Designing Isozyme-Selective Inhibitors That Show Low Affinity For the Ubiquitous Isozyme II also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Carbonic Anhydrase Inhibitors: Clashing with ALA65 As A Means of Designing Isozyme-Selective Inhibitors That Show Low Affinity For the Ubiquitous Isozyme II
(pdb code 2h15). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Carbonic Anhydrase Inhibitors: Clashing with ALA65 As A Means of Designing Isozyme-Selective Inhibitors That Show Low Affinity For the Ubiquitous Isozyme II, PDB code: 2h15: Zinc binding site 1 out of 1 in 2h15Go back to![]() ![]()
Zinc binding site 1 out
of 1 in the Carbonic Anhydrase Inhibitors: Clashing with ALA65 As A Means of Designing Isozyme-Selective Inhibitors That Show Low Affinity For the Ubiquitous Isozyme II
![]() Mono view ![]() Stereo pair view
Reference:
J.Y.Winum,
C.Temperini,
K.El Cheikh,
A.Innocenti,
D.Vullo,
S.Ciattini,
J.L.Montero,
A.Scozzafava,
C.T.Supuran.
Carbonic Anhydrase Inhibitors: Clash with ALA65 As A Means For Designing Inhibitors with Low Affinity For the Ubiquitous Isozyme II, Exemplified By the Crystal Structure of the Topiramate Sulfamide Analogue. J.Med.Chem. V. 49 7024 2006.
Page generated: Thu Oct 17 00:27:41 2024
ISSN: ISSN 0022-2623 PubMed: 17125255 DOI: 10.1021/JM060807N |
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