Atomistry » Zinc » PDB 2c7a-2cij » 2cei
Atomistry »
  Zinc »
    PDB 2c7a-2cij »
      2cei »

Zinc in PDB 2cei: Recombinant Human H Ferritin, K86Q Mutant, Soaked with Zn

Enzymatic activity of Recombinant Human H Ferritin, K86Q Mutant, Soaked with Zn

All present enzymatic activity of Recombinant Human H Ferritin, K86Q Mutant, Soaked with Zn:
1.16.3.1;

Protein crystallography data

The structure of Recombinant Human H Ferritin, K86Q Mutant, Soaked with Zn, PDB code: 2cei was solved by L.Toussaint, R.R.Crichton, J.P.Declercq, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 103.70 / 1.80
Space group F 4 3 2
Cell size a, b, c (Å), α, β, γ (°) 179.419, 179.419, 179.419, 90.00, 90.00, 90.00
R / Rfree (%) 17.4 / 19.2

Zinc Binding Sites:

The binding sites of Zinc atom in the Recombinant Human H Ferritin, K86Q Mutant, Soaked with Zn (pdb code 2cei). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 8 binding sites of Zinc where determined in the Recombinant Human H Ferritin, K86Q Mutant, Soaked with Zn, PDB code: 2cei:
Jump to Zinc binding site number: 1; 2; 3; 4; 5; 6; 7; 8;

Zinc binding site 1 out of 8 in 2cei

Go back to Zinc Binding Sites List in 2cei
Zinc binding site 1 out of 8 in the Recombinant Human H Ferritin, K86Q Mutant, Soaked with Zn


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Recombinant Human H Ferritin, K86Q Mutant, Soaked with Zn within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn210

b:29.4
occ:0.50
O A:HOH2136 1.7 31.8 0.5
OE1 A:GLN86 2.1 31.0 1.0
CD A:GLN86 3.1 27.9 1.0
NE2 A:GLN86 3.5 28.8 1.0
O A:HOH2083 4.2 33.3 1.0
CG A:GLN86 4.5 25.9 1.0
CA A:GLN86 4.9 23.1 1.0
CB A:GLN86 5.0 24.1 1.0
N A:LYS87 5.0 24.0 1.0

Zinc binding site 2 out of 8 in 2cei

Go back to Zinc Binding Sites List in 2cei
Zinc binding site 2 out of 8 in the Recombinant Human H Ferritin, K86Q Mutant, Soaked with Zn


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Recombinant Human H Ferritin, K86Q Mutant, Soaked with Zn within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn211

b:37.4
occ:0.33
O A:HOH2137 2.2 29.8 1.0
OD1 A:ASP131 3.5 31.7 1.0
OG1 A:THR135 3.9 30.3 1.0
OE1 A:GLU134 4.2 28.6 1.0
CG A:ASP131 4.7 30.5 1.0

Zinc binding site 3 out of 8 in 2cei

Go back to Zinc Binding Sites List in 2cei
Zinc binding site 3 out of 8 in the Recombinant Human H Ferritin, K86Q Mutant, Soaked with Zn


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Recombinant Human H Ferritin, K86Q Mutant, Soaked with Zn within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn212

b:25.6
occ:1.00
OE1 A:GLU27 2.1 23.0 1.0
OE1 A:GLU62 2.1 24.2 1.0
ND1 A:HIS65 2.3 27.0 1.0
O A:HOH2138 2.3 26.5 1.0
CD A:GLU27 3.0 23.7 1.0
CD A:GLU62 3.1 24.7 1.0
CE1 A:HIS65 3.2 31.5 1.0
ZN A:ZN213 3.3 27.4 1.0
OE2 A:GLU27 3.3 26.7 1.0
CG A:HIS65 3.4 27.0 1.0
OE2 A:GLU62 3.5 27.2 1.0
CB A:HIS65 3.7 22.2 1.0
OE1 A:GLN141 4.0 32.4 1.0
NE2 A:HIS65 4.3 31.6 1.0
CG A:GLU27 4.4 19.6 1.0
CG1 A:VAL110 4.4 22.7 1.0
CD2 A:HIS65 4.5 30.2 1.0
CG A:GLU62 4.5 22.3 1.0
CA A:GLU62 4.6 20.4 1.0
CB A:GLU27 4.8 19.4 1.0
CB A:GLU62 4.8 20.0 1.0
OE1 A:GLU107 5.0 23.5 1.0

Zinc binding site 4 out of 8 in 2cei

Go back to Zinc Binding Sites List in 2cei
Zinc binding site 4 out of 8 in the Recombinant Human H Ferritin, K86Q Mutant, Soaked with Zn


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Recombinant Human H Ferritin, K86Q Mutant, Soaked with Zn within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn213

b:27.4
occ:1.00
OE2 A:GLU62 2.0 27.2 1.0
OE2 A:GLU107 2.2 29.7 1.0
OE1 A:GLU107 2.3 23.5 1.0
CD A:GLU107 2.6 24.8 1.0
CD A:GLU62 2.9 24.7 1.0
OE1 A:GLU62 3.2 24.2 1.0
ZN A:ZN212 3.3 25.6 1.0
OE1 A:GLN141 3.8 32.4 1.0
CG A:GLU107 4.1 20.9 1.0
O A:HOH2058 4.1 41.7 1.0
CG A:GLU62 4.3 22.3 1.0
NE2 A:GLN141 4.4 26.4 1.0
CE2 A:TYR34 4.5 20.2 1.0
CE1 A:HIS65 4.5 31.5 1.0
CD A:GLN141 4.5 29.4 1.0
ND1 A:HIS65 4.6 27.0 1.0
OH A:TYR34 4.7 25.4 1.0
O A:HOH2138 4.7 26.5 1.0
CB A:GLU107 5.0 20.9 1.0

Zinc binding site 5 out of 8 in 2cei

Go back to Zinc Binding Sites List in 2cei
Zinc binding site 5 out of 8 in the Recombinant Human H Ferritin, K86Q Mutant, Soaked with Zn


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 5 of Recombinant Human H Ferritin, K86Q Mutant, Soaked with Zn within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn214

b:35.6
occ:0.25
NE2 A:HIS173 2.2 32.6 1.0
O A:HOH2139 2.3 13.4 0.2
CE1 A:HIS173 2.9 33.0 1.0
CD2 A:HIS173 3.4 30.5 1.0
ND1 A:HIS173 4.2 32.1 1.0
CG A:HIS173 4.4 27.7 1.0

Zinc binding site 6 out of 8 in 2cei

Go back to Zinc Binding Sites List in 2cei
Zinc binding site 6 out of 8 in the Recombinant Human H Ferritin, K86Q Mutant, Soaked with Zn


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 6 of Recombinant Human H Ferritin, K86Q Mutant, Soaked with Zn within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn215

b:29.2
occ:1.00
O A:HOH2140 2.1 36.0 1.0
NE2 A:HIS60 2.1 32.2 1.0
CE1 A:HIS60 2.4 34.0 1.0
CD2 A:HIS60 3.5 34.1 1.0
ND1 A:HIS60 3.7 34.8 1.0
CG A:HIS60 4.2 27.7 1.0
CD2 A:LEU56 4.4 22.1 1.0
CD1 A:LEU56 4.6 18.1 1.0
CG A:LEU56 4.6 22.1 1.0

Zinc binding site 7 out of 8 in 2cei

Go back to Zinc Binding Sites List in 2cei
Zinc binding site 7 out of 8 in the Recombinant Human H Ferritin, K86Q Mutant, Soaked with Zn


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 7 of Recombinant Human H Ferritin, K86Q Mutant, Soaked with Zn within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn216

b:32.2
occ:1.00
NE2 A:HIS118 2.0 26.0 1.0
O A:HOH2141 2.2 28.9 1.0
SG A:CYS130 2.3 25.1 1.0
CE1 A:HIS118 2.9 27.6 1.0
CD2 A:HIS118 3.0 26.7 1.0
OE2 A:GLU134 3.0 28.3 1.0
CB A:CYS130 3.3 23.0 1.0
ZN A:ZN220 3.3 31.9 1.0
CD A:GLU134 4.0 27.1 1.0
OG1 A:THR122 4.0 28.7 1.0
ND1 A:HIS118 4.0 26.5 1.0
CG A:HIS118 4.1 24.8 1.0
O A:HOH2068 4.1 27.6 1.0
CA A:CYS130 4.3 22.7 1.0
OE1 A:GLU134 4.7 28.6 1.0
CG A:GLU134 4.8 26.9 1.0
C A:CYS130 4.8 23.5 1.0
O A:HOH2042 4.9 50.8 1.0
O A:CYS130 5.0 23.6 1.0

Zinc binding site 8 out of 8 in 2cei

Go back to Zinc Binding Sites List in 2cei
Zinc binding site 8 out of 8 in the Recombinant Human H Ferritin, K86Q Mutant, Soaked with Zn


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 8 of Recombinant Human H Ferritin, K86Q Mutant, Soaked with Zn within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn220

b:31.9
occ:1.00
OE2 A:GLU134 1.9 28.3 1.0
CD A:GLU134 2.7 27.1 1.0
OE1 A:GLU134 2.8 28.6 1.0
ZN A:ZN216 3.3 32.2 1.0
SG A:CYS130 3.7 25.1 1.0
CG A:GLU134 4.2 26.9 1.0
NE2 A:HIS118 4.5 26.0 1.0

Reference:

L.Toussaint, L.Bertrand, L.Hue, R.R.Crichton, J.P.Declercq. High-Resolution X-Ray Structures of Human Apoferritin H-Chain Mutants Correlated with Their Activity and Metal-Binding Sites. J.Mol.Biol. V. 365 440 2007.
ISSN: ISSN 0022-2836
PubMed: 17070541
DOI: 10.1016/J.JMB.2006.10.010
Page generated: Wed Oct 16 22:19:58 2024

Last articles

Fe in 2YXO
Fe in 2YRS
Fe in 2YXC
Fe in 2YNM
Fe in 2YVJ
Fe in 2YP1
Fe in 2YU2
Fe in 2YU1
Fe in 2YQB
Fe in 2YOO
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy