Zinc in PDB 1z7h: 2.3 Angstrom Crystal Structure of Tetanus Neurotoxin Light Chain

All present enzymatic activity of 2.3 Angstrom Crystal Structure of Tetanus Neurotoxin Light Chain:
3.4.24.68;

The structure of 2.3 Angstrom Crystal Structure of Tetanus Neurotoxin Light Chain, PDB code: 1z7h was solved by M.A.Breidenbach, A.T.Brunger, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	38.76 / 2.30
Space group	C 2 2 2
Cell size a, b, c (Å), α, β, γ (°)	105.350, 176.860, 57.230, 90.00, 90.00, 90.00
R / Rfree (%)	21.2 / 21.6

The binding sites of Zinc atom in the 2.3 Angstrom Crystal Structure of Tetanus Neurotoxin Light Chain (pdb code 1z7h). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the 2.3 Angstrom Crystal Structure of Tetanus Neurotoxin Light Chain, PDB code: 1z7h:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the 2.3 Angstrom Crystal Structure of Tetanus Neurotoxin Light Chain


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of 2.3 Angstrom Crystal Structure of Tetanus Neurotoxin Light Chain within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn444 b:95.4 occ:0.56 NE2 A:HIS380 2.5 86.0 1.0 OD2 A:ASP207 2.6 64.5 1.0 OD1 A:ASP207 2.6 63.9 1.0 CG A:ASP207 2.9 63.3 1.0 NE2 A:GLN262 3.1 0.5 0.0 CD1 A:ILE210 3.2 0.6 0.0 CE1 A:HIS380 3.2 86.0 1.0 CD2 A:HIS380 3.7 85.8 1.0 CD A:GLN262 4.1 0.8 0.0 CB A:ASP207 4.4 61.2 1.0 ND1 A:HIS380 4.4 85.9 1.0 OE1 A:GLN262 4.5 0.1 0.0 CG1 A:ILE210 4.6 0.4 0.0 CG A:HIS380 4.7 85.2 1.0

Zinc binding site 2 out of 2 in the 2.3 Angstrom Crystal Structure of Tetanus Neurotoxin Light Chain


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of 2.3 Angstrom Crystal Structure of Tetanus Neurotoxin Light Chain within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn445 b:22.2 occ:1.00 OE1 A:GLU271 2.2 22.1 1.0 NE2 A:HIS233 2.2 18.6 1.0 O A:HOH469 2.2 29.4 1.0 NE2 A:HIS237 2.3 20.6 1.0 OE2 A:GLU271 2.7 26.6 1.0 CD A:GLU271 2.8 25.1 1.0 CD2 A:HIS237 3.0 16.5 1.0 CD2 A:HIS233 3.0 15.6 1.0 CE1 A:HIS233 3.3 20.2 1.0 CE1 A:HIS237 3.4 21.6 1.0 OE2 A:GLU234 4.0 20.4 1.0 O A:HOH561 4.2 31.1 1.0 CG A:HIS237 4.2 15.6 1.0 CG A:HIS233 4.3 18.2 1.0 CG A:GLU271 4.3 25.1 1.0 ND1 A:HIS233 4.3 22.7 1.0 ND1 A:HIS237 4.4 16.2 1.0 OE1 A:GLU234 4.6 19.8 1.0 CD A:GLU234 4.7 18.0 1.0 O A:HOH563 4.8 46.0 1.0 CG2 A:THR274 4.8 17.8 1.0 CB A:GLU271 4.9 21.1 1.0 OH A:TYR375 4.9 55.6 1.0 CA A:GLU271 4.9 23.1 1.0

M.A.Breidenbach, A.T.Brunger. 2.3A Crystal Structure of Tetanus Neurotoxin Light Chain Biochemistry V. 44 7450 2005.
ISSN: ISSN 0006-2960
PubMed: 15895988
DOI: 10.1021/BI050262J