Atomistry » Zinc » PDB 1xv2-1y8j » 1xw7
Atomistry »
  Zinc »
    PDB 1xv2-1y8j »
      1xw7 »

Zinc in PDB 1xw7: Diabetes-Associated Mutations in Human Insulin: Crystal Structure and Photo-Cross-Linking Studies of A-Chain Variant Insulin Wakayama

Protein crystallography data

The structure of Diabetes-Associated Mutations in Human Insulin: Crystal Structure and Photo-Cross-Linking Studies of A-Chain Variant Insulin Wakayama, PDB code: 1xw7 was solved by Z.L.Wan, K.Huang, B.Xu, Y.C.Chu, S.Q.Hu, P.G.Katsoyannis, M.A.Weiss, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 50.10 / 2.30
Space group P 21 3
Cell size a, b, c (Å), α, β, γ (°) 70.852, 70.852, 70.852, 90.00, 90.00, 90.00
R / Rfree (%) 20.5 / 26.9

Other elements in 1xw7:

The structure of Diabetes-Associated Mutations in Human Insulin: Crystal Structure and Photo-Cross-Linking Studies of A-Chain Variant Insulin Wakayama also contains other interesting chemical elements:

Chlorine (Cl) 2 atoms

Zinc Binding Sites:

The binding sites of Zinc atom in the Diabetes-Associated Mutations in Human Insulin: Crystal Structure and Photo-Cross-Linking Studies of A-Chain Variant Insulin Wakayama (pdb code 1xw7). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Diabetes-Associated Mutations in Human Insulin: Crystal Structure and Photo-Cross-Linking Studies of A-Chain Variant Insulin Wakayama, PDB code: 1xw7:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in 1xw7

Go back to Zinc Binding Sites List in 1xw7
Zinc binding site 1 out of 2 in the Diabetes-Associated Mutations in Human Insulin: Crystal Structure and Photo-Cross-Linking Studies of A-Chain Variant Insulin Wakayama


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Diabetes-Associated Mutations in Human Insulin: Crystal Structure and Photo-Cross-Linking Studies of A-Chain Variant Insulin Wakayama within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Zn101

b:4.1
occ:0.33
NE2 B:HIS10 2.0 35.1 1.0
CL B:CL102 2.4 1.4 0.3
CE1 B:HIS10 3.0 37.2 1.0
CD2 B:HIS10 3.0 32.7 1.0
ND1 B:HIS10 4.1 35.3 1.0
CG B:HIS10 4.2 31.8 1.0
O B:LEU6 4.6 31.2 1.0
CB B:LEU6 4.9 30.3 1.0

Zinc binding site 2 out of 2 in 1xw7

Go back to Zinc Binding Sites List in 1xw7
Zinc binding site 2 out of 2 in the Diabetes-Associated Mutations in Human Insulin: Crystal Structure and Photo-Cross-Linking Studies of A-Chain Variant Insulin Wakayama


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Diabetes-Associated Mutations in Human Insulin: Crystal Structure and Photo-Cross-Linking Studies of A-Chain Variant Insulin Wakayama within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Zn201

b:7.7
occ:0.33
NE2 D:HIS10 2.0 33.5 1.0
CL D:CL202 2.3 12.5 0.3
CE1 D:HIS10 2.7 32.3 1.0
CD2 D:HIS10 3.2 34.0 1.0
ND1 D:HIS10 3.9 36.1 1.0
CG D:HIS10 4.2 35.1 1.0
O D:LEU6 4.8 41.0 1.0

Reference:

Z.L.Wan, K.Huang, B.Xu, S.Q.Hu, S.Wang, Y.C.Chu, P.G.Katsoyannis, M.A.Weiss. Diabetes-Associated Mutations in Human Insulin: Crystal Structure and Photo-Cross-Linking Studies of A-Chain Variant Insulin Wakayama Biochemistry V. 44 5000 2005.
ISSN: ISSN 0006-2960
PubMed: 15794638
DOI: 10.1021/BI047585K
Page generated: Wed Oct 16 20:38:28 2024

Last articles

Zn in 9MJ5
Zn in 9HNW
Zn in 9G0L
Zn in 9FNE
Zn in 9DZN
Zn in 9E0I
Zn in 9D32
Zn in 9DAK
Zn in 8ZXC
Zn in 8ZUF
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy