Zinc in PDB 1vfl: Adenosine Deaminase

All present enzymatic activity of Adenosine Deaminase:
3.5.4.4;

The structure of Adenosine Deaminase, PDB code: 1vfl was solved by T.Kinoshita, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	28.43 / 1.80
Space group	P 43 21 2
Cell size a, b, c (Å), α, β, γ (°)	73.726, 73.726, 134.013, 90.00, 90.00, 90.00
R / Rfree (%)	n/a / n/a

The binding sites of Zinc atom in the Adenosine Deaminase (pdb code 1vfl). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Adenosine Deaminase, PDB code: 1vfl:

Zinc binding site 1 out of 1 in the Adenosine Deaminase


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Adenosine Deaminase within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn501 b:24.5 occ:1.00 NE2 A:HIS14 2.0 15.3 1.0 O A:HOH507 2.1 25.9 1.0 NE2 A:HIS12 2.1 17.8 1.0 NE2 A:HIS211 2.2 20.4 1.0 OD1 A:ASP292 2.4 27.6 1.0 CD2 A:HIS14 2.9 17.0 1.0 CE1 A:HIS14 3.0 17.2 1.0 CD2 A:HIS12 3.1 19.4 1.0 CE1 A:HIS12 3.1 21.4 1.0 CD2 A:HIS211 3.1 21.4 1.0 CE1 A:HIS211 3.2 17.7 1.0 CG A:ASP292 3.4 25.6 1.0 OD2 A:ASP292 3.8 26.3 1.0 O A:HOH550 3.9 40.0 1.0 NE2 A:HIS235 3.9 25.5 1.0 CG A:HIS14 4.1 18.1 1.0 ND1 A:HIS14 4.1 16.2 1.0 O A:HOH521 4.1 31.6 1.0 ND1 A:HIS12 4.2 17.6 1.0 CG A:HIS12 4.2 16.9 1.0 CG A:HIS211 4.3 21.0 1.0 ND1 A:HIS211 4.3 19.1 1.0 O A:HOH594 4.5 43.1 1.0 CE1 A:HIS235 4.7 24.8 1.0 CB A:ASP292 4.7 24.9 1.0 CD2 A:HIS235 4.8 25.5 1.0 OD2 A:ASP293 4.8 31.8 1.0 CD A:ARG98 4.9 18.5 1.0 CA A:ASP292 5.0 23.5 1.0 NH2 A:ARG98 5.0 18.1 1.0 O A:HOH605 5.0 44.8 1.0

T.Kinoshita, I.Nakanishi, T.Terasaka, M.Kuno, N.Seki, M.Warizaya, H.Matsumura, T.Inoue, K.Takano, H.Adachi, Y.Mori, T.Fujii. Structural Basis of Compound Recognition By Adenosine Deaminase Biochemistry V. 44 10562 2005.
ISSN: ISSN 0006-2960
PubMed: 16060665
DOI: 10.1021/BI050529E