Zinc in PDB 1u2n: Structure Cbp TAZ1 Domain

All present enzymatic activity of Structure Cbp TAZ1 Domain:
2.3.1.48;

The binding sites of Zinc atom in the Structure Cbp TAZ1 Domain (pdb code 1u2n). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 3 binding sites of Zinc where determined in the Structure Cbp TAZ1 Domain, PDB code: 1u2n:
Jump to Zinc binding site number: 1; 2; 3;

Zinc binding site 1 out of 3 in the Structure Cbp TAZ1 Domain


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure Cbp TAZ1 Domain within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn440 b:0.0 occ:1.00 NE2 A:HIS362 2.1 0.0 1.0 SG A:CYS384 2.3 0.0 1.0 SG A:CYS379 2.3 0.0 1.0 SG A:CYS366 2.3 0.0 1.0 CD2 A:HIS362 2.8 0.0 1.0 HD2 A:HIS362 2.8 0.0 1.0 HB2 A:CYS366 3.1 0.0 1.0 HB2 A:CYS379 3.1 0.0 1.0 CB A:CYS366 3.2 0.0 1.0 CB A:CYS379 3.2 0.0 1.0 HB3 A:CYS366 3.3 0.0 1.0 HE2 A:LYS388 3.3 0.0 1.0 HB3 A:CYS379 3.3 0.0 1.0 CE1 A:HIS362 3.3 0.0 1.0 HH11 A:ARG369 3.4 0.0 1.0 HH12 A:ARG369 3.5 0.0 1.0 CB A:CYS384 3.5 0.0 1.0 HB2 A:CYS384 3.5 0.0 1.0 HE3 A:LYS388 3.6 0.0 1.0 HB3 A:CYS384 3.7 0.0 1.0 HE1 A:HIS362 3.8 0.0 1.0 NH1 A:ARG369 3.8 0.0 1.0 CE A:LYS388 4.0 0.0 1.0 CG A:HIS362 4.1 0.0 1.0 HB3 A:LEU381 4.2 0.0 1.0 ND1 A:HIS362 4.3 0.0 1.0 HZ2 A:LYS388 4.5 0.0 1.0 CA A:CYS379 4.6 0.0 1.0 CA A:CYS366 4.6 0.0 1.0 H A:LEU381 4.7 0.0 1.0 O A:HIS362 4.8 0.0 1.0 HA A:CYS379 4.8 0.0 1.0 HD2 A:LYS388 4.8 0.0 1.0 HB2 A:LEU381 4.8 0.0 1.0 HA A:ALA363 4.8 0.0 1.0 HA A:CYS366 4.8 0.0 1.0 CA A:CYS384 4.9 0.0 1.0 NZ A:LYS388 4.9 0.0 1.0 HD11 A:LEU381 4.9 0.0 1.0

Zinc binding site 2 out of 3 in the Structure Cbp TAZ1 Domain


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Structure Cbp TAZ1 Domain within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn441 b:0.0 occ:1.00 NE2 A:HIS393 2.1 0.0 1.0 SG A:CYS403 2.3 0.0 1.0 SG A:CYS408 2.3 0.0 1.0 SG A:CYS397 2.3 0.0 1.0 CD2 A:HIS393 2.8 0.0 1.0 HD2 A:HIS393 2.8 0.0 1.0 HB2 A:CYS397 3.0 0.0 1.0 HB3 A:CYS403 3.0 0.0 1.0 CB A:CYS403 3.1 0.0 1.0 CB A:CYS397 3.3 0.0 1.0 CE1 A:HIS393 3.3 0.0 1.0 HB2 A:CYS403 3.4 0.0 1.0 CB A:CYS408 3.4 0.0 1.0 HB3 A:CYS408 3.5 0.0 1.0 HB2 A:CYS408 3.6 0.0 1.0 HE1 A:HIS393 3.8 0.0 1.0 HB3 A:CYS397 4.0 0.0 1.0 HB2 A:PRO400 4.1 0.0 1.0 CG A:HIS393 4.1 0.0 1.0 H A:PRO400 4.1 0.0 1.0 HA A:MET394 4.2 0.0 1.0 HA A:CYS397 4.2 0.0 1.0 ND1 A:HIS393 4.3 0.0 1.0 O A:CYS403 4.4 0.0 1.0 CA A:CYS397 4.4 0.0 1.0 CA A:CYS403 4.5 0.0 1.0 O A:PRO400 4.8 0.0 1.0 O A:HIS393 4.8 0.0 1.0 CA A:CYS408 4.8 0.0 1.0 H A:GLN398 4.8 0.0 1.0 N A:PRO400 4.9 0.0 1.0 CA A:PRO400 4.9 0.0 1.0 C A:CYS403 4.9 0.0 1.0 H A:ALA399 5.0 0.0 1.0 HA A:CYS403 5.0 0.0 1.0 HB A:VAL405 5.0 0.0 1.0

Zinc binding site 3 out of 3 in the Structure Cbp TAZ1 Domain


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Structure Cbp TAZ1 Domain within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn442 b:0.0 occ:1.00 NE2 A:HIS417 2.1 0.0 1.0 SG A:CYS426 2.3 0.0 1.0 SG A:CYS429 2.3 0.0 1.0 SG A:CYS421 2.3 0.0 1.0 HE1 A:HIS417 2.4 0.0 1.0 CE1 A:HIS417 2.6 0.0 1.0 HB3 A:CYS426 2.9 0.0 1.0 CB A:CYS426 3.1 0.0 1.0 HB2 A:CYS429 3.3 0.0 1.0 HB2 A:CYS426 3.4 0.0 1.0 CD2 A:HIS417 3.4 0.0 1.0 CB A:CYS429 3.4 0.0 1.0 HB3 A:CYS421 3.7 0.0 1.0 CB A:CYS421 3.7 0.0 1.0 HA A:ARG423 3.8 0.0 1.0 ND1 A:HIS417 3.9 0.0 1.0 HA A:CYS421 3.9 0.0 1.0 HG2 A:ARG423 3.9 0.0 1.0 H A:CYS429 4.0 0.0 1.0 HD2 A:HIS417 4.0 0.0 1.0 HB3 A:CYS429 4.0 0.0 1.0 CG A:HIS417 4.3 0.0 1.0 H A:THR422 4.4 0.0 1.0 CA A:CYS421 4.4 0.0 1.0 H A:ARG423 4.5 0.0 1.0 CA A:CYS426 4.5 0.0 1.0 HA A:TRP418 4.5 0.0 1.0 HB2 A:CYS421 4.5 0.0 1.0 CA A:CYS429 4.6 0.0 1.0 N A:CYS429 4.6 0.0 1.0 HD1 A:HIS417 4.6 0.0 1.0 HA A:CYS429 4.7 0.0 1.0 CA A:ARG423 4.8 0.0 1.0 H A:VAL428 4.8 0.0 1.0 HB A:VAL428 4.9 0.0 1.0 HD2 A:PRO427 4.9 0.0 1.0 CG A:ARG423 4.9 0.0 1.0 O A:HIS417 5.0 0.0 1.0 N A:ARG423 5.0 0.0 1.0 HD1 A:TRP418 5.0 0.0 1.0

R.N.De Guzman, J.M.Wojciak, M.A.Martinez-Yamout, H.J.Dyson, P.E.Wright. Cbp/P300 TAZ1 Domain Forms A Structured Scaffold For Ligand Binding Biochemistry V. 44 490 2005.
ISSN: ISSN 0006-2960
PubMed: 15641773
DOI: 10.1021/BI048161T