Zinc in PDB 1tqw: Golgi Alpha-Mannosidase II in Complex with A Diastereomer of Seleno- Salacinol

All present enzymatic activity of Golgi Alpha-Mannosidase II in Complex with A Diastereomer of Seleno- Salacinol:
3.2.1.114;

The structure of Golgi Alpha-Mannosidase II in Complex with A Diastereomer of Seleno- Salacinol, PDB code: 1tqw was solved by D.A.Kuntz, A.Ghavami, B.D.Johnston, B.M.Pinto, D.R.Rose, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.37 / 1.20
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	69.007, 110.044, 138.946, 90.00, 90.00, 90.00
R / Rfree (%)	17.5 / 18.4

The binding sites of Zinc atom in the Golgi Alpha-Mannosidase II in Complex with A Diastereomer of Seleno- Salacinol (pdb code 1tqw). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Golgi Alpha-Mannosidase II in Complex with A Diastereomer of Seleno- Salacinol, PDB code: 1tqw:

Zinc binding site 1 out of 1 in the Golgi Alpha-Mannosidase II in Complex with A Diastereomer of Seleno- Salacinol


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Golgi Alpha-Mannosidase II in Complex with A Diastereomer of Seleno- Salacinol within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1400 b:6.5 occ:1.00 NE2 A:HIS471 2.0 5.0 1.0 NE2 A:HIS90 2.1 6.0 1.0 OD1 A:ASP92 2.1 7.5 1.0 OD1 A:ASP204 2.1 5.6 1.0 O2 A:BLT1300 2.1 7.4 1.0 CG A:ASP92 2.9 7.0 1.0 CD2 A:HIS471 3.0 5.3 1.0 CE1 A:HIS90 3.0 6.0 1.0 CE1 A:HIS471 3.0 5.5 1.0 CD2 A:HIS90 3.1 5.7 1.0 OD2 A:ASP92 3.1 8.7 1.0 CG A:ASP204 3.1 6.6 1.0 C2 A:BLT1300 3.2 14.3 1.0 C3 A:BLT1300 3.3 15.5 1.0 CB A:ASP204 3.5 6.3 1.0 OD2 A:ASP472 4.0 6.0 1.0 C1 A:BLT1300 4.1 15.1 1.0 ND1 A:HIS471 4.2 5.5 1.0 CG A:HIS471 4.2 4.7 1.0 ND1 A:HIS90 4.2 6.2 1.0 CG A:HIS90 4.2 6.1 1.0 OD2 A:ASP204 4.2 7.4 1.0 O A:HOH2231 4.3 7.5 1.0 CE1 A:HIS470 4.3 5.7 1.0 CB A:ASP92 4.3 6.6 1.0 SE4 A:BLT1300 4.5 6.3 1.0 OH A:TYR269 4.9 8.5 1.0 CA A:ASP92 4.9 5.8 1.0 CA A:ASP204 5.0 6.3 1.0 CG A:ASP472 5.0 5.8 1.0 O1 A:BLT1300 5.0 12.6 1.0 NE2 A:HIS470 5.0 6.2 1.0

D.A.Kuntz, A.Ghavami, B.D.Johnston, B.M.Pinto, D.R.Rose. Insights Into the Mechanism of Drosophila Melanogaster Golgi A-Mannosidase II Through Crystallographic Analysis of the Interactions with Analogues of the Naturally Occurring Glycomimetic Salacinol Tetrahedron Asymmetry V. 16 25 2005.
ISSN: ISSN 0957-4166