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Atomistry » Zinc » PDB 1sxc-1tbo » 1tbb | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Zinc » PDB 1sxc-1tbo » 1tbb » |
Zinc in PDB 1tbb: Catalytic Domain of Human Phosphodiesterase 4D in Complex with RolipramEnzymatic activity of Catalytic Domain of Human Phosphodiesterase 4D in Complex with Rolipram
All present enzymatic activity of Catalytic Domain of Human Phosphodiesterase 4D in Complex with Rolipram:
3.1.4.17; Protein crystallography data
The structure of Catalytic Domain of Human Phosphodiesterase 4D in Complex with Rolipram, PDB code: 1tbb
was solved by
K.Y.J.Zhang,
G.L.Card,
Y.Suzuki,
D.R.Artis,
D.Fong,
S.Gillette,
D.Hsieh,
J.Neiman,
B.L.West,
C.Zhang,
M.V.Milburn,
S.-H.Kim,
J.Schlessinger,
G.Bollag,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 1tbb:
The structure of Catalytic Domain of Human Phosphodiesterase 4D in Complex with Rolipram also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Catalytic Domain of Human Phosphodiesterase 4D in Complex with Rolipram
(pdb code 1tbb). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Catalytic Domain of Human Phosphodiesterase 4D in Complex with Rolipram, PDB code: 1tbb: Jump to Zinc binding site number: 1; 2; Zinc binding site 1 out of 2 in 1tbbGo back to![]() ![]()
Zinc binding site 1 out
of 2 in the Catalytic Domain of Human Phosphodiesterase 4D in Complex with Rolipram
![]() Mono view ![]() Stereo pair view
Zinc binding site 2 out of 2 in 1tbbGo back to![]() ![]()
Zinc binding site 2 out
of 2 in the Catalytic Domain of Human Phosphodiesterase 4D in Complex with Rolipram
![]() Mono view ![]() Stereo pair view
Reference:
K.Y.J.Zhang,
G.L.Card,
Y.Suzuki,
D.R.Artis,
D.Fong,
S.Gillette,
D.Hsieh,
J.Neiman,
B.L.West,
C.Zhang,
M.V.Milburn,
S.-H.Kim,
J.Schlessinger,
G.Bollag.
A Glutamine Switch Mechanism For Nucleotide Selectivity By Phosphodiesterases Mol.Cell V. 15 279 2004.
Page generated: Wed Oct 16 19:04:58 2024
ISSN: ISSN 1097-2765 PubMed: 15260978 DOI: 10.1016/J.MOLCEL.2004.07.005 |
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